Evidence map›Paper›PMID 40975058›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2025

EROdicating arterial thrombosis with a novel endoplasmic reticulum oxidoreductase 1α inhibitor.

Timur O Yarovinsky, Anish V Sharda, John Hwa

Abstract read
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Timur O YarovinskyYale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA; Yale Cooperative Center of Excellence in Hematology, Yale School of Medicine, New Haven, CT, USA.
Anish V ShardaYale Cooperative Center of Excellence in Hematology, Yale School of Medicine, New Haven, CT, USA; Section of Hematology, Yale Cancer Center, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
John HwaYale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA; Yale Cooperative Center of Excellence in Hematology, Yale School of Medicine, New Haven, CT, USA. Electronic address: john.hwa@yale.edu.

Funding

Yale Cooperative Hematology Specialized Core CenterU54DK106857 · NIDDK · YALE UNIVERSITY · PI JOHN HWA, Diane S Krause · 2015 to 2026
$9.7M
Platelet Mitochondrial Function in Health and DiseaseR01HL122815 · NHLBI · YALE UNIVERSITY · PI HWA, JOHN · 2015 to 2023
$3.7M
Platelets in vascular injury repairR01HL150515 · NHLBI · YALE UNIVERSITY · PI HWA, JOHN · 2020 to 2023
$2.3M
Molecular Mechanisms Underlying Endothelial Weibel-Palade Body Biogenesis and ExocytosisK08HL150246 · NHLBI · YALE UNIVERSITY · PI SHARDA, ANISH VAIBHAV · 2021 to 2025
$901k
NHLBI NIH HHS K08 HL150246NHLBI NIH HHS R01 HL122815NHLBI NIH HHS R01 HL150515NIDDK NIH HHS U54 DK106857
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40975058
PMCPMC12848167

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.