ReviewMaterials today. Bio2025
Zinc oxide nanoparticles for skin wound healing: A systematic review from the perspective of disease types.
Review in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Infections in Burn Patients: Pathophysiology, Prevention, and Contemporary Therapeutic Strategies in the Era of Antimicrobial Resistance.Infectious diseases and therapy · 2026Review
- Photocatalytic and anticancer potentials of green-synthesized neodymium-doped zinc oxide nanoparticles.3 Biotech · 2026Article
- Article
- Biogenic Zinc Oxide Nanoparticles for Skin Disorders: Mechanistic Insights, Translational Challenges, and Future Prospects.Biological trace element research · 2026Review
- Biogenic Zinc Oxide Nanoparticles for Skin Disorders: Mechanistic Insights, Translational Challenges, and Future Prospects.Biological trace element research · 2026Review
- Data-Driven Engineering of Antimicrobial Nanomaterials for Food Safety and Biomedical Systems.Nanomaterials (Basel, Switzerland) · 2026Review
- Biosynthesis of ecofriendly antibacterial nanoparticles with healing effects in a murine diabetic skin infection model.Scientific reports · 2026Article
- Electrospun Poly(caprolactone)/Poly(ethylene oxide) Membranes Incorporating Green-Synthesized Zinc Oxide Nanoparticles for Enhanced Wound Healing Applications.Small science · 2026Article
- Article
- Selected Deposition Techniques and the Effect of Doping on the Properties of Thin ZnO Films: A Literature Review.Materials (Basel, Switzerland) · 2026Review
- Simulation-guided design of peptide-metal coordination interfaces for next-generation metallo-immunotherapy.Nano convergence · 2026Review
- Advances in Nanotechnology-Assisted Delivery of TCM-Derived Bioactive Compounds for Wound Repair.Pharmaceutics · 2026Review
- Electrospun PVA Nanofibers Co-Loaded with Atorvastatin and Zinc Oxide for Antibacterial and In Vitro Wound Healing Applications.Biomedicines · 2026Article
- A novel green synthesized ZnO-based antimicrobial nanocomposite: synergistic action, in vitro cytotoxicity, and molecular docking studies of ceftazidime, metformin, and chitosan against multidrug-resistant Salmonella enterica.Microbial cell factories · 2026Article
- Unveiling the potential of inorganic nanoparticle-based scaffolds in wound healing: advances in antimicrobial and regenerative strategies.Nanoscale advances · 2026Review
- Green Synthesis of ZnO Nanoparticles: A Sustainable Approach for Wound Care.Nanotechnology, science and applications · 2026Review
- Agricultural and Agro-Industrial Residues as Sustainable Sources of Next-Generation Biomedical Materials: Advances, Challenges, and Perspectives.Life (Basel, Switzerland) · 2025Review
- Bioprinted Recombinant Human-Collagen-Based In Vitro Skin Models for Assessing Effects of Nano-ZnO on Dermis.Gels (Basel, Switzerland) · 2025Article
- Recent advances in polymer-based drug delivery systems for atopic dermatitis: enhancing therapeutic efficacy and outcomes.Materials today. Bio · 2025Review
- Mechanism of Action of Zinc Oxide Nanoparticles as an Antibacterial Agent AgainstBiomolecules · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The skin, the body's largest organ, acts as the primary defense against external environmental threats and is crucial for maintaining homeostasis. It encounters various challenges in healing diverse wound types, including mechanical injuries, diabetic ulcers, and burns. Zinc oxide nanoparticles (ZnO NPs) are increasingly recognized for their unique properties and potential in promoting skin wound healing. However, the effects and specific mechanisms of ZnO NPs in pathological microenvironments remain poorly understood. This systematic review aims to elucidate the roles of ZnO NPs in the wound healing processes associated with mechanical injuries, diabetic ulcers, and burns. Relevant literature was identified using defined search terms related to skin wounds treated by ZnO NPs. The findings across studies show that ZnO-loaded dressings exhibit superior efficacy in promoting tissue regeneration. At appropriate concentrations, ZnO NPs demonstrate superior performance compared to non-ZnO materials in promoting wound healing. Additionally, ZnO NP-containing materials possess characteristics such as antibacterial and anti-inflammatory properties. The mechanisms underlying the promotion of wound healing by ZnO in mechanical traumas, diabetic ulcers, and burns are summarized, highlighting its promising potential for tissue regeneration applications.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.