Evidence map›Paper›PMID 40977962›Full record

ArticleIranian journal of medical sciences2025

The Role of Functional Polymorphisms of Apoptotic

Afrooz Daneshparvar, Iman Jamhiri, Farhad Handjani, Nasrin Hamidizadeh

Abstract read
In one paragraph

Article in Iranian journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Afrooz DaneshparvarMolecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Iman JamhiriMolecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Farhad HandjaniDepartment of Dermatology, University Hospitals Coventry and Warwickshire, Coventry, UK.
Nasrin HamidizadehMolecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Vitiligo is an autoimmune skin disorder in which apoptosis plays an exceptionally vital role in its occurrence. Research has shown a strong association between the presence of polymorphisms and the occurrence of diseases. This study aimed to determine the association of Methods: This cross-sectional study utilized the tetra-primer amplification refractory mutation system polymerase chain reaction (ARMS PCR) in a cohort of vitiligo patients referred to the esteemed dermatology department of Shahid Faqihi Hospital in Shiraz between 2022 and 2023. The Chi square test and Results: From 112 healthy individuals and 107 vitiligo patients, our research uncovered a significant association between the C allele ( Conclusion: The results showed that

Indexed as

bcl-2-Associated X ProteinProto-Oncogene Proteins c-bcl-2VitiligoAdolescentAdultApoptosisCross-Sectional StudiesFemaleGenetic Predisposition to DiseaseHumansIranMaleMiddle AgedPolymorphism, Single NucleotideBAX protein, humanbcl-2-Associated X ProteinBCL2 protein, humanProto-Oncogene Proteins c-bcl-2ApoptosisB-cell lymphoma-2Bcl-2 associated XPolymorphismVitiligo

Identifiers

PMID40977962
PMCPMC12449581

What Socratic holds

Textmetadata
LicenceCC BY-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.