Evidence mapPaperPMID 40978074Full record

ReviewJournal of multidisciplinary healthcare2025

Mapping the Research Landscape of Polyphenols in Osteoarthritis: A Bibliometric Perspective.

Weibei Sheng, Siyang Cao, Haotian Qin, Peng Liu, Deli Wang, Hui Zeng, Jian Weng, Fei Yu

Abstract readReview
In one paragraph

Review in Journal of multidisciplinary healthcare, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Weibei ShengDepartment of Bone & Joint Surgery, National & Local Joint Engineering Research Center of Orthopaedic Biomaterials, Shenzhen Key Laboratory of Orthopaedic Diseases and Biomaterials Research, Peking University Shenzhen Hospital, Shenzhen, 518036, People's Republic of China.ORCID 0009-0002-0679-1950
Siyang CaoDepartment of Bone & Joint Surgery, National & Local Joint Engineering Research Center of Orthopaedic Biomaterials, Shenzhen Key Laboratory of Orthopaedic Diseases and Biomaterials Research, Peking University Shenzhen Hospital, Shenzhen, 518036, People's Republic of China.ORCID 0000-0001-7409-3746
Haotian QinDepartment of Bone & Joint Surgery, National & Local Joint Engineering Research Center of Orthopaedic Biomaterials, Shenzhen Key Laboratory of Orthopaedic Diseases and Biomaterials Research, Peking University Shenzhen Hospital, Shenzhen, 518036, People's Republic of China.
Peng LiuDepartment of Bone & Joint Surgery, National & Local Joint Engineering Research Center of Orthopaedic Biomaterials, Shenzhen Key Laboratory of Orthopaedic Diseases and Biomaterials Research, Peking University Shenzhen Hospital, Shenzhen, 518036, People's Republic of China.
Deli WangDepartment of Bone & Joint Surgery, National & Local Joint Engineering Research Center of Orthopaedic Biomaterials, Shenzhen Key Laboratory of Orthopaedic Diseases and Biomaterials Research, Peking University Shenzhen Hospital, Shenzhen, 518036, People's Republic of China.
Hui ZengDepartment of Orthopedic Trauma, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, People's Republic of China.
Jian Weng *Department of Bone & Joint Surgery, National & Local Joint Engineering Research Center of Orthopaedic Biomaterials, Shenzhen Key Laboratory of Orthopaedic Diseases and Biomaterials Research, Peking University Shenzhen Hospital, Shenzhen, 518036, People's Republic of China.
Fei Yu *Department of Spine Surgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, 518035, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyphenols, a diverse group of plant-derived compounds known for their antioxidant and anti-inflammatory properties, have garnered increasing attention for their therapeutic potential in osteoarthritis (OA). However, a comprehensive bibliometric analysis of the research landscape in this field has been lacking. This study aimed to systematically evaluate global research trends, knowledge structure, and emerging hotspots related to polyphenols in OA. Publications from 2000 to 2025 were retrieved from the Web of Science Core Collection and analyzed using bibliometric tools such as VOSviewer and CiteSpace. A total of 1,436 publications were identified, demonstrating a steady rise in annual output, with China and the United States emerging as the most prolific contributors. Keyword co-occurrence and citation burst analyses revealed that curcumin, resveratrol, EGCG, inflammation, oxidative stress, and cartilage degeneration are central research themes. Notably, recent trends highlight increasing interest in ferroptosis, gut microbiota, and targeted drug delivery systems in the context of polyphenol-based OA therapies. This bibliometric analysis provides a comprehensive overview of the current status and developmental trajectory of polyphenol research in OA, offering valuable insights to guide future studies and foster interdisciplinary collaboration.

Indexed as

bibliometric analysisinflammationosteoarthritisoxidative stresspolyphenolsresearch trends

Identifiers

PMID40978074
PMCPMC12450029

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.