Evidence map›Paper›PMID 40978172›Full record

ArticleData in brief2025

Integrative experimental and computational dataset for repurposed antibiofilm drug candidates targeting quorum sensing.

Abdelsattar M Omar, Khadijah A Mohammad, Mohammed Almalki, Khalid O Abulnaja, Sabrin R M Ibrahim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Data in brief, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Abdelsattar M OmarDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Khadijah A MohammadDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Mohammed AlmalkiDepartment of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, 21589 Saudi Arabia.
Khalid O AbulnajaDepartment of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, 21589 Saudi Arabia.
Sabrin R M IbrahimDepartment of Chemistry, Preparatory Year Program, Batterjee Medical College, Jeddah 21442, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This data article presents an integrated dataset combining experimental in vitro biofilm assays and Data Description: A library of 29 small-molecule compounds (including in-house synthesized analogs and pharmacologically active drugs) was screened for antibiofilm efficacy against Reuse Potential: These data can be used to explore structure-activity relationships for antibiofilm activity, to validate new computational models of biofilm inhibition, or to inform further drug repurposing efforts. All raw data (biofilm assay measurements, MIC values, docking poses and scores, simulation files, and ADMET profiles) are provided to facilitate reuse and reproducibility. No conclusions or interpretive analysis are included, making this a purely descriptive report of the dataset.

Indexed as

Antibiofilm agentsAnti-virulenceBacterial biofilmsDrug repurposingHealth and well-beingMolecular dockingQuorum sensing inhibition

Identifiers

PMID40978172
PMCPMC12446609

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.