Evidence map›Paper›PMID 40978436›Full record

ArticleACS omega2025

MALDI-TOF MS and Machine Learning Explanations for the Detection of SARS-CoV‑2 Infection in Human Plasma: Fingerprints as a Strategy for Risk Assessment.

Meritxell Deulofeu, Esteban García-Cuesta, Eladia María Peña-Méndez, José Elías Conde-González, Orlando Jiménez-Romero, Enrique Verdú, Maria Teresa Serrando, Victoria Salvadó, Pere Boadas-Vaello

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Meritxell DeulofeuResearch Group of Clinical Anatomy, Embryology and Neuroscience (NEOMA), Department of Medical Sciences, University of Girona, Girona 17003, Catalonia, Spain.
Esteban García-CuestaDepartment of Artificial Intelligence, Universidad Politécnica de Madrid, Madrid 28223, Spain.
Eladia María Peña-MéndezDepartment of Chemistry, Analytical Chemistry Division, Faculty of Sciences, University of La Laguna, San Cristóbal de La Laguna, Tenerife 38204, Spain.ORCID https://orcid.org/0000-0002-1474-3134
José Elías Conde-GonzálezDepartment of Chemistry, Analytical Chemistry Division, Faculty of Sciences, University of La Laguna, San Cristóbal de La Laguna, Tenerife 38204, Spain.
Orlando Jiménez-RomeroResearch Group of Clinical Anatomy, Embryology and Neuroscience (NEOMA), Department of Medical Sciences, University of Girona, Girona 17003, Catalonia, Spain.
Enrique VerdúResearch Group of Clinical Anatomy, Embryology and Neuroscience (NEOMA), Department of Medical Sciences, University of Girona, Girona 17003, Catalonia, Spain.
Maria Teresa SerrandoResearch Group of Clinical Anatomy, Embryology and Neuroscience (NEOMA), Department of Medical Sciences, University of Girona, Girona 17003, Catalonia, Spain.
Victoria SalvadóDepartment of Chemistry, Faculty of Science, University of Girona, Girona 17071, Catalonia, Spain.ORCID https://orcid.org/0000-0002-1171-141X
Pere Boadas-VaelloResearch Group of Clinical Anatomy, Embryology and Neuroscience (NEOMA), Department of Medical Sciences, University of Girona, Girona 17003, Catalonia, Spain.ORCID https://orcid.org/0000-0001-8497-1207

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic proved to be a major public health challenge that had an enormously disruptive effect on the operational management of hospitals. It became especially important to find both diagnostic and prognostic methods for risk severity evaluation. Here, a MALDI-TOF MS method for the profiling of plasma samples combined with machine learning (ML) and its explanations was developed to identify SARS-CoV-2 infection while also allowing for the classification of patients by the severity of the disease. A prospective study of the most important

Identifiers

PMID40978436
PMCPMC12444529

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.