Evidence map›Paper›PMID 40978585›Full record

ArticleBioinformation2025

Evaluation of salivary biomarker interleukin-6 in oral squamous cell carcinoma and its clinical correlation.

Dipak Chaudhari, Shilpa Motghare, Vikas Pandey, Gunmeek Kaur, Sameer Gupta, Saptadisha Rakshit, Miral Mehta, Bhumika J Patel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dipak ChaudhariDepartment of General Dentistry, Smilebuilderz LLC, Lancaster, Pennsylvania, US.
Shilpa MotghareDepartment of Pathology, SRVS, Government Medical College, Shivpuri (Madhya Pradesh), India.
Vikas PandeyDepartmnet of Pathology, Goverment Medical College, Satna, Madhya Pradesh, India.
Gunmeek KaurDepartment of Oral and Maxillofacial Surgery, Luxmi Bai Dental College and Hospital, Patiala, Punjab, India.
Sameer GuptaDepartment of Oral & Maxillofacial Surgery, Inderprastha Dental College and Hospital, Sahibabad , Ghaziabad , Uttar Pradesh - 201010, Ghaziabad, India.
Saptadisha RakshitIntern batch BDS 2020, Kalinga Institute of Dental Sciences, KIIT Deemed to be University, Odisha, India.
Miral MehtaDepartment of Pediatric and Preventive Dentistry, Karnavati School of Dentistry, Karnavati University, Gandhinagar, Gujarat,India.
Bhumika J PatelDepartment of Dentistry, Howard University, College of Dentistry, Washington DC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral Squamous Cell Carcinoma (OSCC) is a prevalent malignancy with high morbidity. Hence, this cross-sectional study evaluated salivary interleukin-6 (IL-6) levels in 30 OSCC patients versus 30 healthy controls. IL-6 levels were significantly higher in OSCC patients and increased progressively with advancing clinical stages. A strong positive correlation was found between IL-6 levels and disease stage (r = 0.82, p < 0.001). Salivary IL-6 shows promise as a non-invasive biomarker for OSCC detection and progression monitoring.

Indexed as

cancer staginginterleukin-6non-invasive diagnosticsOral squamous cell carcinomasalivary biomarkers

Identifiers

PMID40978585
PMCPMC12449527

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.