Evidence map›Paper›PMID 40978756›Full record

ArticleFrontiers in medicine2025

Acidosis and in-hospital mortality in patients with pulmonary hypertension: a retrospective cohort study based on the MIMIC-IV database.

Yuheng Ye, Di Yin, Yi Wang, Jiancheng Lin, Jiayan Sun, Xiaowan Wang, Qiang Guo

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Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yuheng YeDepartment of Critical Care Medicine, The Fourth Affiliated Hospital of Soochow University, Suzhou, China.
Di YinDepartment of Critical Care Medicine, The Fourth Affiliated Hospital of Soochow University, Suzhou, China.
Yi WangDepartment of Critical Care Medicine, The Fourth Affiliated Hospital of Soochow University, Suzhou, China.
Jiancheng LinDepartment of Critical Care Medicine, The Fourth Affiliated Hospital of Soochow University, Suzhou, China.
Jiayan SunDepartment of Critical Care Medicine, The Fourth Affiliated Hospital of Soochow University, Suzhou, China.
Xiaowan WangDepartment of Critical Care Medicine, The Fourth Affiliated Hospital of Soochow University, Suzhou, China.
Qiang GuoDepartment of Critical Care Medicine, The Fourth Affiliated Hospital of Soochow University, Suzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pulmonary hypertension (PH) is a life-threatening disease. However, acidosis could be used to predict the prognosis of critically ill patients. Consequently, this study was to identify the link between acidosis and in-hospital death of PH patients based on the Medical Information Mart for Intensive Care-IV (MIMIC-IV) database. Methods: Eligible subjects from the MIMIC-IV database were selected for this analysis (2008-2019), after which differences in variables between the survival statuses of PH patients were evaluated. Subsequently, employing three weighted multiple logistic regression models to investigate the link between acidosis and PH. Further, risk stratification analysis were applied to explore the relationships between acidosis as well as other covariates and PH. Results: Total 2,530 PH patients (247 dead and 2,283 live or 157 acidosis and 2,373 non-acidosis) were included in the analysis. Next, the result indicated highly significant differences between the dead and live groups in factors such as acidosis and sepsis ( Conclusion: This study identified acidosis was a risk factor for PH, highlighting the importance of monitoring in PH patients at risk for acidosis.

Indexed as

acidosisassociation analysismortalitypulmonary hypertensionrisk stratification analysis

Identifiers

PMID40978756
PMCPMC12446051

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.