Evidence map›Paper›PMID 40979047›Full record

ReviewCureus2025

Advancing Care in Alzheimer's Disease: Current Treatments and Their Impact on Quality of Life.

Leyla Yashaeva, Melissa Montoya, Juee Joshi, Aliyah Stephens, Olivia McNulty, Gurjinder Kaur

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Leyla YashaevaBasic Biomedical Sciences, Touro College of Osteopathic Medicine, Middletown, USA.
Melissa MontoyaBasic Biomedical Sciences, Touro College of Osteopathic Medicine, Middletown, USA.
Juee JoshiBasic Biomedical Sciences, Touro College of Osteopathic Medicine, Middletown, USA.
Aliyah StephensBasic Biomedical Sciences, Touro College of Osteopathic Medicine, Middletown, USA.
Olivia McNultyPhysiology, Touro College of Osteopathic Medicine, Middletown, USA.
Gurjinder KaurPhysiology, Touro College of Osteopathic Medicine, Middletown, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by memory deficits and cognitive decline. It is currently the most common cause of dementia globally and carries a significant disease burden, given the rising aging population worldwide. Although AD is debilitating for the patient, the complex nature of the disease is also a source of tremendous mental distress for caregivers. Finding, understanding, and evaluating the best treatments can be challenging and overwhelming when coping with a life-changing diagnosis of AD. Although there is currently no definite cure for AD, all the discussed treatments aim to improve a patient's quality of life and attenuate the time spent in disability. This study compiles and discusses the risks, benefits, and efficacy of all currently available treatments for AD, including treatments that target the control of cognitive and non-cognitive symptoms. Additionally, the manuscript discusses investigational therapeutics, including small molecules and immunotherapies in phase 2 or 3 clinical trials, and assesses non-pharmacological interventions that may alleviate disease burden.

Indexed as

alzheimer's diseaseamyloid plaquescognitive declinedementia treatmentdisease-modifying drugsfda-approved therapiesneurodegenerationtau protein

Identifiers

PMID40979047
PMCPMC12446084

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.