Evidence map›Paper›PMID 40979151›Full record

ReviewWorld journal of orthopedics2025

Therapeutic potential of traditional Chinese medicine for inflammatory bone diseases: Elucidating molecular mechanisms and insights.

Jing-Shun Lu, Min Yang, Zeng-Gao Han, Chen-Yu Song, Nurjamal Sarbay, Kai-Yang Wang

Abstract readReview
In one paragraph

Review in World journal of orthopedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jing-Shun LuDepartment of Orthopedics, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu 241000, Anhui Province, China.
Min YangDepartment of Traditional Chinese Medicine, Meilong Community Health Service Center of Minhang District, Shanghai 200233, China.
Zeng-Gao HanYunnan Southern Central Hospital, Honghe Hani and Yi Autonomous Prefecture First People's Hospital, Mengzi 661000, Yunnan Province, China.
Chen-Yu SongTrauma Center, Tongji Hospital, School of Medicine, Tongji University, Shanghai 200065, China.
Nurjamal SarbayKirgiz Institute of Ethnic Medicine, People's Hospital of Kizilsu Kirgiz Autonomous Prefecture, Atushi 845350, Xinjiang Uygur Autonomous Region, China.
Kai-Yang WangDepartment of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China. ortho_wang@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bone diseases constitute a category of chronic inflammatory disorders, with the primary pathological characteristic being the impact of chronic inflammation on bone metabolism and remodeling. It leads to pain, spinal joint deformities, and functional impairments. Common clinical types of inflammatory bone diseases include rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. However, there is a paucity of effective clinical treatments for inflammatory bone diseases, and pharmacological interventions are frequently associated with intolerable side effects. Traditional Chinese medicine (TCM) has a long-standing history and proven efficacy in managing inflammatory bone diseases. In recent years, an increasing number of studies have highlighted the potential of TCM in this context. This article systematically evaluates the application of TCM in treating inflammatory bone diseases, emphasizing the underlying molecular mechanisms of its anti-inflammatory effects. By elucidating the specific targets of TCM in the treatment of rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis, we aim to provide novel insights into the further exploration of TCM's role in clinical application for inflammatory bone diseases.

Indexed as

Ankylosing spondylitisInflammationInflammatory arthritisOsteoarthritisRheumatoid arthritisTraditional Chinese medicine

Identifiers

PMID40979151
PMCPMC12444264

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.