SynthesisFrontiers in aging neuroscience2025
Cognitive behavioral therapy for anxiety and depression symptoms in people of Parkinson's disease: a systematic review and meta-analysis.
Synthesis in Frontiers in aging neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Bridging the Rural Mental Health Gap: Telehealth Delivery of Specialized CBT and MBCT for Veterans With Parkinson's Disease.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: We aim to conducted a systematic review and meta-analysis of published RCTs (Randomized Controlled Trials, RCTs) to quantify the effects of CBT (Cognitive behavioral therapy, CBT), including both remote and in-person modalities, on anxiety, depressive symptoms, and QoL (Quality of Life, QoL) in people with PD (Parkinson's disease, PD). Methods: The systematic review and meta-analysis followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Eight databases were systematically searched for existing RCTs of CBT in people of PD published in English or Chinese. Searches were updated to February 29, 2024. Methodological quality was appraised with the Cochrane Risk of Bias tool. A meta-analysis of comparative effects was performed using the Review Manager v. 5.4 software. Results: 16 RCTs were included in the study. The studies involved a total of 682 participants, the mean age of participants ranged from 43 to 85. Depression scores of people in the CBT intervention group were significantly improved (SMD: -1.01, 95CI [-1.27, -0.74], Conclusion: This systematic review and meta-analysis provide evidence that CBT intervention significantly improved anxiety and depression in People of PD compared to the control group, whether through offline or remote intervention. No improvement effect of CBT intervention on the QoL of People of PD was found. In the future application of telemedicine, interdisciplinary interventions should be explored to improve the motor and non-motor symptoms and QoL of People of PD. Systematic review registration: https://www.crd.york.ac.uk/prospero/#recordDetails. Identifier: CRD42024526608.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.