Evidence map›Paper›PMID 40979257›Full record

Trial reportRespirology case reports2025

Integrative Supportive Care Trial to Enhance Physical Activity in Malignant Pleural Effusion-Protocol for the ISC-TEAM/AMPLE-5 Randomised Controlled Trial.

Bianca M Iacopetta, Chloe Charlesworth, Emily Jeffery, Lauren J Breen, Ai Ling Tan, Joanne McVeigh, Kevin Murray, Rob U Newton, Y C Gary Lee, Carolyn J Peddle-Mcintyre

Abstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Respirology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bianca M IacopettaInstitute for Respiratory Health, Pleural Medicine Unit Perth Australia.ORCID https://orcid.org/0009-0003-7510-5261
Chloe CharlesworthCentre for Innovative Pleural Research, Sir Charles Gairdner Hospital Perth Australia.
Emily JefferySchool of Population Health Faculty of Health Sciences, Curtin University Perth Australia.ORCID https://orcid.org/0000-0002-9463-3196
Lauren J BreenSchool of Population Health Faculty of Health Sciences, Curtin University Perth Australia.ORCID https://orcid.org/0000-0002-0463-0363
Ai Ling TanInstitute for Respiratory Health, Pleural Medicine Unit Perth Australia.ORCID https://orcid.org/0009-0004-8956-0537
Joanne McVeighSchool of Allied Health Faculty of Health Sciences, Curtin University Perth Australia.ORCID https://orcid.org/0000-0002-2446-3814
Kevin MurraySchool of Population and Global Health University of Western Australia Perth Australia.ORCID https://orcid.org/0000-0002-8856-6046
Rob U NewtonExercise Medicine Research Institute School of Medical and Health Sciences, Edith Cowan University Perth Australia.ORCID https://orcid.org/0000-0003-0302-6129
Y C Gary LeeInstitute for Respiratory Health, Pleural Medicine Unit Perth Australia.ORCID https://orcid.org/0000-0002-0036-511X
Carolyn J Peddle-McintyreInstitute for Respiratory Health, Pleural Medicine Unit Perth Australia.ORCID https://orcid.org/0000-0001-9913-4022

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Malignant pleural effusion (MPE) heralds advanced cancer with poor patient outcomes. High symptom burden of weight loss, fatigue, breathlessness, distress, and anxiety leaves many patients unable to participate in desired activities of daily life and is associated with poor outcomes. Freedom from symptoms and maintaining daily activities are the key wishes of patients and carers. For the best outcome, accessible services aimed at prevention and management of malnutrition, care of psychological well-being, and support for increasing physical activity are required. Methods: The Integrative Supportive Care Trial to Enhance physical Activity in Malignant pleural effusion (ISC-TEAM) study is a two-armed, parallel group randomised controlled trial. Participants ( Discussion: This randomised trial will evaluate the effects of a multidisciplinary supportive care program in MPE aimed at improving participants ability to engage in physical activities. Trial Registration: Australian New Zealand Clinical Trials Registry: ACTRN12624000038594; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=386529&isReview=true.

Indexed as

malignant pleural effusionmultidisciplinary teamphysical activitysupportive care

Identifiers

PMID40979257
PMCPMC12444935

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.