Evidence map›Paper›PMID 40979635›Full record

ReviewFrontiers in bioengineering and biotechnology2025

Nanocarrier-mediated drug delivery systems for spinal cord injury treatment.

Yajun Cheng, Rui Wang, Xiaoyi Zhou, Hao Jiang, Ming Li, Xianzhao Wei

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yajun Cheng *Department of Orthopaedics, First Affiliated Hospital, Naval Medical University (Second Military Medical University), Shanghai, China.
Rui Wang *Department of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Naval Medical University, Shanghai, China.
Xiaoyi Zhou *Department of Orthopaedics, First Affiliated Hospital, Naval Medical University (Second Military Medical University), Shanghai, China.
Hao Jiang *Spine Tumor Center, Changzheng Hospital, Naval Medical University, Shanghai, China.
Ming LiDepartment of Orthopaedics, First Affiliated Hospital, Naval Medical University (Second Military Medical University), Shanghai, China.
Xianzhao WeiDepartment of Orthopaedics, First Affiliated Hospital, Naval Medical University (Second Military Medical University), Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spinal cord injury is a severe neurological condition that frequently. Results in lasting motor and sensory dysfunction. Traditional drug therapies have shown limited efficacy in addressing the complexities of spinal cord injury. This limitation highlighting the urgent need for innovative treatment strategies. In recent years, nanocarrier-mediated systems have garnered significant attention due to their superior drug delivery capabilities and targeting precision. This review summarizes the latest advancements in the application of nanocarriers for the treatment of spinal cord injuries, discussing various types of nanocarriers, drug loading and capacity and release profiles, as well as targeted delivery strategies. The insights aim to establish a theoretical foundation for future research and clinical applications in this critical area of medicine.

Indexed as

drug deliverynanocarriersnanoparticles and nanomaterialsspinal cord injurytargeted therapy

Identifiers

PMID40979635
PMCPMC12447078

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.