Evidence map›Paper›PMID 40979787›Full record

ReviewWorld journal of emergency medicine2025

Long-term cardiovascular outcomes and risk factors in adult sepsis survivors: a systematic review and meta-analysis.

Zesheng Wu, Fanghui Chen, Chen Xiao, Xue Zhao, Yuansheng Xu, Jinyan Fang, Yinyan Shao

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zesheng Wu1Department of Emergency Medicine, Affiliated Hangzhou First People's Hospital, School of Medicine, WestlakeUniversity, Hangzhou 310006, China.
Fanghui Chen1Department of Emergency Medicine, Affiliated Hangzhou First People's Hospital, School of Medicine, WestlakeUniversity, Hangzhou 310006, China.
Chen Xiao1Department of Emergency Medicine, Affiliated Hangzhou First People's Hospital, School of Medicine, WestlakeUniversity, Hangzhou 310006, China.
Xue Zhao1Department of Emergency Medicine, Affiliated Hangzhou First People's Hospital, School of Medicine, WestlakeUniversity, Hangzhou 310006, China.
Yuansheng Xu1Department of Emergency Medicine, Affiliated Hangzhou First People's Hospital, School of Medicine, WestlakeUniversity, Hangzhou 310006, China.
Jinyan Fang2Department of Physical Examination Center, Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou 310006, China.
Yinyan Shao3Department of Physical Examination Center, Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou 310006, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSepsis may increase the risk of long-term cardiovascular outcomes. This study aims to investigate association between sepsis survivorship and cardiovascular outcomes and to identify risk factors.

methodsWe conducted a comprehensive systematic search of MEDLINE, EMBASE, the Cochrane Library, Wanfang, and CNKI from database inception through May 2025, without language restrictions. The primary outcome was a composite of myocardial infarction, stroke, congestive heart failure, or cardiovascular death. To evaluate the association between sepsis survivors and cardiovascular outcomes, we calculated cumulative incidence rates and hazard ratios (

resultsTwenty-five observational studies comprising 7,525,271 participants were included. The pooled cumulative incidence of major cardiovascular events was 9.0% (95%

conclusionAdult sepsis survivors may face significantly increased risks of long-term cardiovascular outcomes. Both common cardiovascular risk factors and sepsis-related pathophysiological changes contribute to this association.

Indexed as

Cardiovascular outcomesRisk factorsSepsisSepsis survivorsStroke

Identifiers

PMID40979787
PMCPMC12444231

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.