ArticleInfection and drug resistance2025
Comorbidity Clusters and Immune Profiles in Hospitalized People with HIV: A Retrospective Analysis at a Tertiary Care Center in Eastern China.
Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Antiretroviral therapy (ART) has shifted hospitalization causes in people with HIV (PWH) from AIDS-related to non-AIDS-related events. Data on comorbidity profiles and clinical characteristics of hospitalized PWH remain limited. Therefore, this study analyzes comorbidities and clinical characteristics of PWH in eastern China to understand the regional burden of comorbidities and inform clinical practice and regional hospital management. Methods: This retrospective study included 593 hospitalized PWH. Demographic, clinical, and laboratory data, along with HIV-related medical history, were extracted from medical records. Diagnoses of comorbidities were based on established criteria. Clinical characteristics were compared across comorbidity groups. Results: Among 593 participants, comorbidities were categorized into three groups: Non-AIDS-Defining Diseases (NADs, n=241), Opportunistic Infections (OI, n=204), and Malignancies (n=111). PWH with malignancies were significantly older (median age 58 years) than those with OI (43 years, Conclusion: NADs have emerged as the leading cause of hospitalization among PWH. For PWH who receive stable ART, remain at risk for NADs, warranting regular screening to prevent advanced disease. Routine monitoring of CD4+ T cell counts and CD4:CD8 ratios may facilitate improved cancer and OI screening strategies for individuals with persistently low ratios of CD4/CD8 or ART-naïve.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.