Evidence mapPaperPMID 40980108Full record

ReviewFrontiers in drug safety and regulation2023

Conducting and interpreting disproportionality analyses derived from spontaneous reporting systems.

Paola Maria Cutroneo, Daniele Sartori, Marco Tuccori, Salvatore Crisafulli, Vera Battini, Carla Carnovale, Concetta Rafaniello, Annalisa Capuano, Elisabetta Poluzzi, Ugo Moretti and 1 more

Abstract readReview
In one paragraph

Review in Frontiers in drug safety and regulation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 3 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Paola Maria CutroneoSicily Pharmacovigilance Regional Centre, University Hospital of Messina, Messina, Italy.
Daniele SartoriUppsala Monitoring Centre, Uppsala, Sweden.
Marco TuccoriUnit of Adverse Drug Reaction Monitoring, University Hospital of Pisa, Pisa, Italy.
Salvatore CrisafulliDepartment of Medicine, University of Verona, Verona, Italy.
Vera BattiniDepartment of Biomedical and Clinical Sciences, Pharmacovigilance & Clinical Research, International Centre for Pesticides and Health Risk Prevention, ASST Fatebenefratelli-Sacco, Università degli Studi di Milano, Milan, Italy.
Carla CarnovaleDepartment of Biomedical and Clinical Sciences, Pharmacovigilance & Clinical Research, International Centre for Pesticides and Health Risk Prevention, ASST Fatebenefratelli-Sacco, Università degli Studi di Milano, Milan, Italy.
Concetta RafanielloDepartment of Experimental Medicine, Section of Pharmacology "L. Donatelli", University of Campania "Luigi Vanvitelli", Napoli, Italy.
Annalisa CapuanoDepartment of Experimental Medicine, Section of Pharmacology "L. Donatelli", University of Campania "Luigi Vanvitelli", Napoli, Italy.
Elisabetta PoluzziDepartment of Medical and Surgical Sciences, Pharmacology Unit, Alma Mater Studiorum, University of Bologna, Bologna, Italy.
Ugo MorettiDepartment of Medicine, University of Verona, Verona, Italy.
Emanuel RaschiDepartment of Medical and Surgical Sciences, Pharmacology Unit, Alma Mater Studiorum, University of Bologna, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spontaneous reporting systems remain pivotal for post-marketing surveillance and disproportionality analysis (DA) represents a recognized approach for early signal detection. Although DAs cannot be used

Indexed as

adverse drug reactionsdisproportionalitydisproportionality analysesSDRsignal detectionspontaneous reporting database

Identifiers

PMID40980108
PMCPMC12443087

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.