Evidence map›Paper›PMID 40980110›Full record

ReviewFrontiers in drug safety and regulation2023

Promising treatment biomarkers in asthma.

Barbara Bonnesen, Jens-Ulrik S Jensen, Alexander G Mathioudakis, Alexandru Corlateanu, Pradeesh Sivapalan

Abstract readReview
In one paragraph

Review in Frontiers in drug safety and regulation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Barbara BonnesenDepartment of Medicine, Section of Respiratory Medicine, Herlev-Gentofte Hospital, Hellerup, Denmark.
Jens-Ulrik S JensenDepartment of Medicine, Section of Respiratory Medicine, Herlev-Gentofte Hospital, Hellerup, Denmark.
Alexander G MathioudakisDivision of Immunology, Immunity to Infection and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester, United Kingdom.
Alexandru CorlateanuDepartment of Respiratory Medicine, Nicolae Testemiţanu State University of Medicine and Pharmacy, Chisinau, Moldova.
Pradeesh SivapalanDepartment of Medicine, Section of Respiratory Medicine, Herlev-Gentofte Hospital, Hellerup, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthma is a highly heterogenous disease which researchers over time have attempted to classify into different phenotypes and endotypes to improve diagnosis, prognosis and treatment. Earlier classifications based on reaction to environmental allergens, age, sex and lung function have evolved, and today, the use of precision medicine guided by biomarkers offers new perspectives on asthma management. Identifying biomarkers that may reveal the underlying pathophysiology of the disease will help to select the patients who will benefit most from specific treatments. This review explores the classification of asthma phenotypes and focuses on the most recent advances in using biomarkers to guide treatment.

Indexed as

asthmaasthma treatmentbiomarkerpersonalized medicinephenotype

Identifiers

PMID40980110
PMCPMC12443126

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.