ArticleNeuro-oncology advances
Impact of the COVID-19 pandemic on primary brain tumor incidence and management: Decisions that went right.
Article in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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9 authors.
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Abstract
Background: The COVID-19 pandemic drastically altered cancer care. Prior reports demonstrated reduced screenings, diagnoses, and disrupted treatment regimens due to multifactorial reasons. We aim to analyze whether the same effects occurred within neuro-oncology. Methods: This analysis included 70 131 patients with primary brain tumors from the SEER database from 2016 to 2021 identified via ICD10 code. The pre-COVID era was 2016-2019, peak-COVID was 2020, and post-COVID was 2021. Multivariate analysis was performed using logistic regression for binary variables and linear regression for continuous. Covariates controlled for were age at diagnosis, sex, and race. NCI SEER*Stat version 8.4.0 was used to calculate incidence rates age-adjusted to the 2000 US standard population and reported per 100 000 persons. Results: Although there was a decrease in the age-adjusted incidence of primary brain tumors between 2016 and 2021, the number of malignant brain tumors remained stable, and this change was likely driven by a reduction in benign tumor incidence. Regarding treatment, in 2020 and 2021 all malignant brain tumors (2020 OR[95%CI]: 1.11[1.02-1.22], 2021: 1.10[1.01-1.020]) and glioblastoma patients (2020 OR[95%CI]: 1.12[1.01-1.26], 2021: 1.13[1.01-1.27]) underwent increased surgical resections, compared to pre-COVID years. Time from diagnosis to treatment decreased for glioblastoma patients in 2020, compared to pre-COVID (Estimate [95%CI]: -1.25 [-1.71 to -0.78]). No treatment changes were noted for benign brain tumors. Conclusion: Malignant tumors, like glioblastoma, maintained a stable incidence due to their aggressive symptoms, though treatment patterns shifted. These findings reveal that the management of malignant brain tumors during the COVID-19 pandemic was effectively prioritized while maintaining quality of care.
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