Evidence map›Paper›PMID 40980912›Full record

ArticleAntimicrobial agents and chemotherapy2025

Pharmacokinetics of sulbactam-durlobactam in patients with

Nazanin Pouya, Natalie A Finch, Alejandro Granillo, Adarsh Bhimraj, Vincent H Tam, William R Miller

Abstract readCase Reports
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Treating Extensively Drug-ResistantPathogens (Basel, Switzerland) · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nazanin PouyaDepartment of Pharmacy Practice and Translational Research, University of Houston College of Pharmacy, Houston, Texas, USA.
Natalie A FinchDepartment of Pharmacy, Houston Methodist Hospital, Houston, Texas, USA.
Alejandro GranilloDivision of Infectious Diseases, Department of Internal Medicine, Houston Methodist Hospital, Houston, Texas, USA.
Adarsh BhimrajDivision of Infectious Diseases, Department of Internal Medicine, Houston Methodist Hospital, Houston, Texas, USA.
Vincent H TamDepartment of Pharmacy Practice and Translational Research, University of Houston College of Pharmacy, Houston, Texas, USA.ORCID 0000-0001-7071-5376
William R MillerDivision of Infectious Diseases, Department of Internal Medicine, Houston Methodist Hospital, Houston, Texas, USA.ORCID 0000-0002-1518-2973

Funding

Personalized Antimicrobial Combinations to Combat ResistanceR01AI140287 · NIAID · UNIVERSITY OF HOUSTON · PI VINCENT H TAM · 2018 to 2026
$5.9M
Emergence of TonB-dependent receptor mediated cefiderocol resistance among multidrug-resistant (MDR) Pseudomonas aeruginosa clinical isolates.R21AI175821 · NIAID · METHODIST HOSPITAL RESEARCH INSTITUTE · PI MILLER, WILLIAM R · 2023 to 2024
$467k
NIAID NIH HHS R01 AI140287NIAID NIH HHS R21 AI175821NIH HHS R01AI140287NIH HHS R21AI175821
6 · The paper itself

Abstract

Two adult patients with ventriculitis due to

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial AgentsAzabicyclo CompoundsCerebral VentriculitisSulbactamAdultHumansAnti-Bacterial AgentsAzabicyclo CompoundsdurlobactamSulbactambeta-lactambeta-lactamase inhibitorCNS penetrationgram-negative bacteria

Identifiers

PMID40980912
PMCPMC12587607

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.