Evidence map›Paper›PMID 40981390›Full record

ArticleAudiology research2025

A Novel 1259 bp Intragenic Deletion in the

David Oaxaca-Castillo, Laura Taño-Portuondo, Montserrat Rodríguez-Ballesteros, Gerardo Pérez-Mendoza, Igrid García-González, Jorge Canto-Herrera, María Domínguez-Ruiz, Doris Pinto-Escalante, Orlando Vargas-Sierra, Damaris Estrella-Castillo and 4 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Audiology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Recent Progress in Mechanism-Based Therapies forInternational journal of molecular sciences · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

David Oaxaca-CastilloLaboratorio de Genética, Centro de Investigaciones Regionales, Unidad Biomédica, Universidad Autónoma de Yucatán, Calle 43 #613 x 96, Colonia Inalámbrica, Mérida 97225, Mexico.
Laura Taño-PortuondoLaboratorio de Genética, Centro de Investigaciones Regionales, Unidad Biomédica, Universidad Autónoma de Yucatán, Calle 43 #613 x 96, Colonia Inalámbrica, Mérida 97225, Mexico.ORCID 0009-0004-8010-3428
Montserrat Rodríguez-BallesterosServicio de Genética, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.
Gerardo Pérez-MendozaLaboratorio de Genética, Centro de Investigaciones Regionales, Unidad Biomédica, Universidad Autónoma de Yucatán, Calle 43 #613 x 96, Colonia Inalámbrica, Mérida 97225, Mexico.
Igrid García-GonzálezLaboratorio de Genética, Centro de Investigaciones Regionales, Unidad Biomédica, Universidad Autónoma de Yucatán, Calle 43 #613 x 96, Colonia Inalámbrica, Mérida 97225, Mexico.
Jorge Canto-HerreraLaboratorio de Genética, Centro de Investigaciones Regionales, Unidad Biomédica, Universidad Autónoma de Yucatán, Calle 43 #613 x 96, Colonia Inalámbrica, Mérida 97225, Mexico.ORCID 0009-0005-4232-7583
María Domínguez-RuizServicio de Genética, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.ORCID 0000-0002-7583-0370
Doris Pinto-EscalanteLaboratorio de Genética, Centro de Investigaciones Regionales, Unidad Biomédica, Universidad Autónoma de Yucatán, Calle 43 #613 x 96, Colonia Inalámbrica, Mérida 97225, Mexico.
Orlando Vargas-SierraLaboratorio de Genética, Centro de Investigaciones Regionales, Unidad Biomédica, Universidad Autónoma de Yucatán, Calle 43 #613 x 96, Colonia Inalámbrica, Mérida 97225, Mexico.
Damaris Estrella-CastilloUnidad Universitaria de Rehabilitación, Facultad de Medicina, Universidad Autónoma de Yucatán, Avenida Itzáes No. 498, Centro, Mérida 97000, Mexico.ORCID 0000-0001-9381-8263
Paola López-GonzálezDiagnósticos Moleculares y Genéticos, DIMYGEN Laboratorio S.C.P., Calle 78 No. 578 x 13-1 y 128, Residencial Pensiones, Mérida 97217, Mexico.
Javier E Sosa-EscalanteDiagnósticos Moleculares y Genéticos, DIMYGEN Laboratorio S.C.P., Calle 78 No. 578 x 13-1 y 128, Residencial Pensiones, Mérida 97217, Mexico.ORCID 0000-0002-3077-9217
Ignacio Del CastilloServicio de Genética, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.ORCID 0000-0003-1188-3665
Lizbeth González-HerreraLaboratorio de Genética, Centro de Investigaciones Regionales, Unidad Biomédica, Universidad Autónoma de Yucatán, Calle 43 #613 x 96, Colonia Inalámbrica, Mérida 97225, Mexico.ORCID 0000-0002-8620-3954

Funding

Autonomous University of Yucatán CIRB-2023-0018Instituto de Salud Carlos III PI24/00397
6 · The paper itself

Abstract

Hearing loss is a genetically heterogeneous sensory defect for which biallelic pathogenic variants in the

Indexed as

connexin-26GJB2 genehearing lossintragenic deletionSanger sequencing

Identifiers

PMID40981390
PMCPMC12452471

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.