Evidence map›Paper›PMID 40983166›Full record

ArticleChest2026

Association Between Poor Olfaction and Lower Pulmonary Function in Older Adults.

Guoyong Ding, Jingjing Xia, Jayant M Pinto, Zahia Esber, Yaqun Yuan, Chenxi Li, Qu Tian, Anna Kucharska-Newton, Eleanor M Simonsick, Honglei Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chest, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Guoyong DingDepartment of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing, MI; Department of Epidemiology, School of Public Health (G. D.), Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Jingjing XiaDepartment of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing, MI.
Jayant M PintoSection of Otolaryngology-Head and Neck Surgery, Department of Surgery, The University of Chicago Medicine and Biological Sciences, Chicago, IL.
Zahia EsberDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Wayne State University School of Medicine, Detroit, MI.
Yaqun YuanDepartment of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing, MI.
Chenxi LiDepartment of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing, MI.
Qu TianTranslational Gerontology Branch, Intramural Research Program of the National Institute on Aging, National Institutes of Health, Baltimore, MD.
Anna Kucharska-NewtonDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Eleanor M SimonsickTranslational Gerontology Branch, Intramural Research Program of the National Institute on Aging, National Institutes of Health, Baltimore, MD.
Honglei ChenDepartment of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing, MI. Electronic address: chenho19@msu.edu.

Funding

ChicAgo Center for Health and EnvironmenT (CACHET)P30ES027792 · UNIVERSITY OF CHICAGO · 2025 to 2025
$1.6M
DYNAMICS OF HEALTH .AGING . AND BODY COMPOSITION /Pittsburgh/-260962101N01AG062101 · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 1996 to 2004
$996k
DYNAMICS OF HEALTH . AGING . AND BODY COMPOSITION /Memphis/-26062103N01AG062103 · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · 1996 to 2004
$793k
Poor sense of smell and the health of older adultsR01AG071517 · MICHIGAN STATE UNIVERSITY · 2025 to 2025
$489k
HEALTH ABC--COORDINATING UNIT /California/-260062106N01AG062106 · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · 1996 to 2004
$109k
NIA NIH HHS N01 AG062101NIA NIH HHS N01 AG062103NIA NIH HHS N01 AG062106NIA NIH HHS R01 AG028050NIA NIH HHS R01 AG071517NIEHS NIH HHS P30 ES027792NINR NIH HHS R01 NR012459
6 · The paper itself

Abstract

backgroundOlfaction may be associated with lung health because of the anatomic and functional connections between the upper and lower airways, but empirical evidence is lacking. RESEARCH QUESTION: Is poor olfaction associated with lower pulmonary function in older adults? STUDY DESIGN AND

methodsThis study included 1,951 participants from the Health, Aging, and Body Composition Study who completed the 12-item Brief Smell Identification Test (B-SIT) in clinical visit year 3 (1999-2000) and at least 1 valid spirometry test in the year 5, 8, or 10 clinical visits. The mean (SD) age at the baseline spirometry test was 74.4 (2.8) years. Olfaction was categorized as good (B-SIT score, 11-12), moderate (B-SIT score, 9-10), or poor (B-SIT score, 0-8). We used multivariable joint models to assess the associations of olfaction with FEV

resultsParticipants with poor olfaction demonstrated lower FEV

interpretationOur results indicate that poor olfaction is associated with worse pulmonary function in older adults. Future studies should confirm our findings and investigate potential mechanisms.

Indexed as

LungOlfaction DisordersSmellAgedAged, 80 and overFemaleForced Expiratory VolumeHumansMaleRespiratory Function TestsSpirometryVital CapacityFEV(1)FEV(1) to FVC ratioFVCjoint modelolder adultsolfactionpulmonary function

Identifiers

PMID40983166
PMCPMC12507451

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.