Evidence map›Paper›PMID 40984936›Full record

ArticleCureus2025

Functional Assessment Over Time Using Electroretinograms: A Case Report of a Pediatric Patient With Central Retinal Artery Occlusion.

Yuro Igawa, Kazuhiro Ueyama, Hiroshi Ishikawa, Junji Kanno, Midori Tachibana, Kei Shinoda

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuro IgawaDepartment of Ophthalmology, Saitama Medical University, Saitama, JPN.
Kazuhiro UeyamaDepartment of Ophthalmology, Saitama Medical University, Saitama, JPN.
Hiroshi IshikawaDepartment of Ophthalmology, Saitama Medical University, Saitama, JPN.
Junji KannoDepartment of Ophthalmology, Saitama Medical University, Saitama, JPN.
Midori TachibanaDepartment of Ophthalmology, Saitama Medical University, Saitama, JPN.
Kei ShinodaDepartment of Ophthalmology, Saitama Medical University, Saitama, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report describes a rare instance of central retinal artery occlusion (CRAO) in a 10-year-old girl, emphasizing the importance of electroretinography (ERG) in monitoring retinal function over time. CRAO, which is typically prevalent in middle-aged and older adults, manifests abruptly with painless vision loss and is seldom reported in the pediatric population, making this case particularly noteworthy. Unlike adults, whose CRAO often stems from atherosclerosis or emboli, pediatric cases may involve different etiologies, such as trauma or congenital defects like atrial septal defects. In this case, the patient experienced sudden vision loss in her right eye following ocular trauma. Initial examinations showed a cherry red spot and retinal swelling, with normal anterior segments and visual acuity of 0.4 in the affected eye. Over a period of six months, assessments included cone ERG, which documented a decline in both a-wave and b-wave amplitudes, indicative of progressive retinal dysfunction affecting the inner layer. Despite the retinal degeneration, the patient's visual acuity improved slightly, likely due to the collateral circulation from the ciliary artery, which is not typically affected by CRAO. This case underscores the utility of ERG in providing a comprehensive evaluation of retinal health that cannot be discerned from visual acuity alone. The findings suggest that despite the structural damage, certain retinal functions can be preserved, offering insights into potential therapeutic targets. This case adds valuable information to the limited literature on pediatric CRAO and supports the need for further research to better understand its pathophysiology and management. The role of the ciliary artery in maintaining visual function despite central retinal artery compromise is a salient area for future studies, with the potential to inform treatment strategies for preserving vision in similar cases.

Indexed as

central retinal artery occlusioncraoelectroretinographyergretina

Identifiers

PMID40984936
PMCPMC12450115

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.