ReviewCureus2025
A Review of Weight Loss With Glucagon-Like Peptide 1 Agonist Therapy: Is There a Role for Its Preoperative Use in Gynecology?
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Answer to the letter to the editor of E. Mohebi, et al. concerning "The safety and accuracy of radiation-free spinal navigation using a short, scoliosis-specific BoneMRI-protocol, compared to CT" by P.P.G. Lafranca, et al. (Eur spine J [2025]; doi:10.1007/s00586-025-09151-x).European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glucagon-like peptide 1 (GLP-1) agonist use for weight loss has skyrocketed. Dramatic weight loss with GLP-1 agonist use is frequently portrayed on social media. Contrastingly, such extensive weight loss has not been reported in published randomized controlled trials on weight loss after GLP-1 agonist use. However, these medications have been used for perioperative optimization in bariatric and orthopedic surgery. Therefore, there may be some applications in other surgical fields, particularly for reducing weight prior to surgery. Rising rates of obesity warrant the evaluation of preoperative GLP-1 agonists in gynecology to reduce surgery morbidity. We reviewed clinical trial-level data on GLP-1 agonist-related weight loss in hopes of completing a cost-effectiveness analysis. However, our review demonstrated that there are no current publications in patients undergoing benign hysterectomy to complete a robust cost-effectiveness analysis. Despite this, this review revealed important information about the use of GLP-1 agonists. It informs both clinicians and patients about realistic expectations for weight loss and how these therapies may be considered in a surgical framework. The goal of this narrative review is to report expected weight loss after these medications, frame the current data into a clinical context in gynecology, and demonstrate the urgent need to scientifically evaluate the role of preoperative GLP-1 agonist use in patients undergoing hysterectomy.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.