Evidence map›Paper›PMID 40984976›Full record

ArticleiScience2025

Pistachio leaf waste transformed into a gut-targeted bioactive phytocomplex.

Mariarita Spampinato, Salvatore Furnari, Laura Siracusa, Giuseppe A Malfa, Alfio Distefano, Enrico La Spina, Massimo Gulisano, Pio Maria Furneri, Virginia Fuochi, Ignazio A Barbagallo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mariarita SpampinatoDepartment of Biomedical and Biotechnological Sciences, University of Catania, via Santa Sofia 97, 95124 Catania, Italy.
Salvatore FurnariDepartment of Biomedical and Biotechnological Sciences, University of Catania, via Santa Sofia 97, 95124 Catania, Italy.
Laura SiracusaInstitute of Biomolecular Chemistry, National Research Council (ICB-CNR), via Paolo Gaifami 18, 95126 Catania, Italy.
Giuseppe A MalfaDepartment of Drug and Health Sciences, University of Catania, V.le A. Doria 6, 95125 Catania, Italy.
Alfio DistefanoDepartment of Biomedical and Biotechnological Sciences, University of Catania, via Santa Sofia 97, 95124 Catania, Italy.
Enrico La SpinaDepartment of Biomedical and Biotechnological Sciences, University of Catania, via Santa Sofia 97, 95124 Catania, Italy.
Massimo GulisanoDepartment of Drug and Health Sciences, University of Catania, V.le A. Doria 6, 95125 Catania, Italy.
Pio Maria FurneriDepartment of Biomedical and Biotechnological Sciences, University of Catania, via Santa Sofia 97, 95124 Catania, Italy.
Virginia FuochiDepartment of Biomedical and Biotechnological Sciences, University of Catania, via Santa Sofia 97, 95124 Catania, Italy.
Ignazio A BarbagalloDepartment of Biomedical and Biotechnological Sciences, University of Catania, via Santa Sofia 97, 95124 Catania, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human gut microbiota is integral to host physiology, influencing immune responses, metabolic regulation, and digestion. Disruptions in this microbial community are linked to inflammatory and metabolic disorders. In this study, we explored the potential of pistachio leaf extract (PLE), a polyphenol-rich natural product, to support gut health. The extract, obtained from

Indexed as

Health sciencesMicrobiologyNutritionPhytochemistry

Identifiers

PMID40984976
PMCPMC12450566

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.