Evidence map›Paper›PMID 40986036›Full record

ArticleJournal of neural transmission (Vienna, Austria : 1996)2026

Mediating roles of attention-deficit/hyperactivity disorder symptom severity and self-control on the relationship between adverse childhood experiences and adult aggression.

Johannes Merscher, Wolfgang Retz, Petra Retz-Junginger, Steffen Barra

Abstract read
In one paragraph

Article in Journal of neural transmission (Vienna, Austria : 1996), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Johannes MerscherInstitute for Forensic Psychology and Psychiatry, Saarland University, Homburg, Germany. johannes.merscher@uni-saarland.de.ORCID http://orcid.org/0009-0008-7065-6626
Wolfgang RetzInstitute for Forensic Psychology and Psychiatry, Saarland University, Homburg, Germany.
Petra Retz-JungingerInstitute for Forensic Psychology and Psychiatry, Saarland University, Homburg, Germany.
Steffen BarraInstitute for Forensic Psychology and Psychiatry, Saarland University, Homburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous research has identified attention-deficit/hyperactivity disorder (ADHD), adverse childhood experiences (ACEs), and low self-control as risk factors for aggressive behavior. While associations among these variables have been widely documented, the underlying mechanisms remain unclear. Grounded in the General Theory of Crime, this study investigates the relationship between ACEs and aggression, with a particular focus on the mediating roles of ADHD and self-control in a serial mediation model. Based on the theoretically grounded assumption that ACEs contribute to adult ADHD symptomatology, which impairs self-control and predicts aggressive behavior, this study examines the dynamic interplay among these constructs in a mixed-gender sample of 350 participants aged 18 to 76 years (M = 34.9, SD = 13.1). Serial mediation analyses revealed positive associations between ACEs and aggression, as well as between ACEs and ADHD. Additionally, a significant positive correlation was observed between ADHD and aggression. Conversely, self-control exhibited a negative relationship with both ADHD and aggression. Mediation analyses indicated that ADHD and self-control partially mediated the link between ACEs and aggression in adults irrespective of gender and age. Our results suggest that violence prevention efforts could benefit from early interventions aimed at reducing ACEs, diagnostic assessment and treatment of ADHD symptoms, and therapeutic interventions designed to enhance self-control and thereby mitigate their impact on aggression.

Indexed as

Adverse Childhood ExperiencesAggressionAttention Deficit Disorder with HyperactivitySelf-ControlAdolescentAdultAgedFemaleHumansMaleMiddle AgedSeverity of Illness IndexYoung AdultADHDAdverse childhood experiencesAggressionSelf-control

Identifiers

PMID40986036
PMCPMC12999651

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.