Evidence mapPaperPMID 40986254Full record

GuidelineClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2025

SEOM-GEICO clinical guidelines on endometrial cancer (2025).

Sara Pérez Ramírez, Alejandro Pérez Fidalgo, María Pilar Barretina Ginesta, Ana De Juan Ferré, Lorena Fariñas Madrid, Alejandro Gallego Martínez, Fernando Gálvez Montosa, Ainhoa Madariaga, Teresa Martin Gómez, Marta Gil-Martin

Abstract readPractice Guideline
In one paragraph

Guideline in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sara Pérez RamírezDepartment of Medical Oncology, Hospital General Universitario Gregorio Marañón, Madrid, Spain. sperezramirez85@gmail.com.ORCID http://orcid.org/0000-0002-3558-8241
Alejandro Pérez FidalgoDepartment of Medical Oncology, Hospital Clínico Universitario de Valencia, INCLIVA, Valencia, Spain.
María Pilar Barretina GinestaDepartment of Medical Oncology, Catalan Institute of Oncology Girona, IDIBGI-CERCA, Girona, Spain.
Ana De Juan FerréDepartment of Medical Oncology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain.
Lorena Fariñas MadridDepartment of Medical Oncology, Hospital Universitario Vall d'Hebron, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.
Alejandro Gallego MartínezDepartment of Medical Oncology, Cancer Center Clínica Universidad de Navarra (CCUN), Madrid, Spain.
Fernando Gálvez MontosaDepartment of Medical Oncology, Hospital Universitario de Jaén, Jaén, Spain.
Ainhoa MadariagaDepartment of Medical Oncology, Hospital Universitario, 12 de Octubre, Madrid, Spain.
Teresa Martin GómezDepartment of Medical Oncology, Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain.
Marta Gil-MartinDepartment of Medical Oncology, Institut Català d'Oncologia L'Hospitalet- IDIBELL, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometrial cancer (EC) is the most common gynecological malignancy in developed countries. Although most cases are diagnosed at an early stage, prognosis in case of relapse or metastasis remains poor. Molecular characterization of EC is highly recommended as it allows more accurate risk stratification and may modify treatment recommendations. The updated FIGO 2023 staging of EC highlights the importance of traditional clinicopathological factors, while underlining the need for molecular classification to predict outcomes. In early-stage EC, standard treatment consists of total hysterectomy and bilateral salpingo-oophorectomy. Lymph node evaluation remains controversial, as the benefits of systematic lymphadenectomy are unclear. Adjuvant treatment, consisting of radiotherapy, brachytherapy, and chemotherapy, should be chosen according to risk category. In women with advanced or recurrent EC, the combination of carboplatin and paclitaxel has long been standard treatment. However, therapeutic options have changed recently due to advances in immunotherapy. The aim of this guideline is to summarize the current evidence for the diagnosis, treatment, and follow-up of EC, and to provide evidence-based recommendations for clinical practice.

Indexed as

Endometrial NeoplasmsChemotherapy, AdjuvantFemaleHumansHysterectomyLymph Node ExcisionNeoplasm StagingDiagnosisEndometrial cancerFollow-upGuidelineTreatment

Identifiers

PMID40986254
PMCPMC12630260

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.