Evidence mapPaperPMID 40988749Full record

ArticleFrontiers in medicine2025

Diabetes mellitus and pregnancy in Wolfram syndrome type 1: a case report with review of clinical and pathophysiological aspects.

Amelia Caretto, Francesca Scarascia Mugnozza, Fanny Valsecchi, Erika Pedone, Mirko Pozzoni, Susanna Rosa, Andrea Laurenzi, Giulio Frontino, Raniero Chimienti, Lorenzo Piemonti and 1 more

Abstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Amelia CarettoDiabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Francesca Scarascia MugnozzaVita-Salute San Raffaele University, Milan, Italy.
Fanny ValsecchiVita-Salute San Raffaele University, Milan, Italy.
Erika PedoneDiabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Mirko PozzoniDepartment of Obstetrics and Gynaecology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Susanna RosaDepartment of Obstetrics and Gynaecology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Andrea LaurenziDiabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Giulio FrontinoDepartment of Pediatrics, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Raniero ChimientiDiabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Lorenzo PiemontiDiabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Marina ScaviniDiabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wolfram syndrome type 1 (WS1) is a rare genetic disorder characterized primarily by non-autoimmune diabetes mellitus, optic atrophy, deafness, and diabetes insipidus. It may include other endocrine, urological, psychiatric, and neurological disorders. The syndrome arises from mutations in the

Indexed as

automated insulin deliveryfertilitypregestational diabetespregnancyrare diseasetherapyWolfram syndrome

Identifiers

PMID40988749
PMCPMC12450988

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.