ReviewClinical neuropsychiatry2025
Autonomic Nervous System and Possible Determinants of Social Behavior: A Systematic Review of its Relationship Among Psychopathy, Compassion, and Theory of Mind.
Review in Clinical neuropsychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Sensitive alterations in the balance between physiological changes may be a relevant factor in the expression of social behavior and are systematically reported in a broad spectrum of psychopathological conditions. Among these, psychopathy, compassion and theory of mind hold a prominent role in social interaction. Biomarkers associated with such individual characteristics could represent an ambitious breakthrough in clinical practice, both diagnostically and therapeutically. The aim of this work is to evaluate the available evidence published in the past 20 years in order to investigate the relationship between the autonomic nervous system and the aforementioned individual characteristics. Method: A literature search was conducted using dedicated search engines, including Pubmed, Scopus, and Google Scholar. The review focused on evidence published over the last two decades, from 2003 to 2024. Results: Individuals with high trait psychopathy show reduced activation in skin conductance. This attenuation results in lower sensitivity to learning through fear conditioning mechanisms and an impaired ability to process affective stimuli. Studies focusing on compassion, while showing less variability in measures and proposed tasks, have revealed a possible effect of time in terms of efficacy, with therapeutic intervention programs (of at least 2 weeks' duration) also showing an impact on autonomic indices. Studies focused on theory of mind highlighted mixed findings and may require further investigation. Conclusions: Interpretation of results may be limited by the numerosity and demographic characteristics of the participants, the plurality of autonomic indices used, and the heterogeneity of the proposed tasks. The ability to modify sensitivity to autonomic changes intentionally through possible specific therapeutic interventions could be a potential clinical goal.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.