ArticleNeurosurgical review2025
Efficacy of microvascular decompression versus percutaneous balloon compression in trigeminal neuralgia: a propensity-matched retrospective analysis.
Article in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Multimodal MRI fusion and three-dimensional reconstruction for preoperative assessment of neurovascular compression in trigeminal neuralgia: A retrospective study.Neurosurgical review · 2026Article
- Outcomes of repeat microvascular decompression versus percutaneous balloon compression for recurrent trigeminal neuralgia.Neurosurgical review · 2026Observational
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
To compare the efficacy and safety of microvascular decompression (MVD) and percutaneous balloon compression (PBC) in trigeminal neuralgia (TN) management, focusing on pain relief, recurrence, complications, and patient satisfaction.A retrospective cohort of 226 MVD and 127 PBC patients was analyzed after propensity score matching (PSM). Clinical baseline characteristics, surgical details, and postoperative follow-up information were collected. The primary outcome of this study was recurrent pain of TN, and the secondary outcome was facial numbness dissatisfaction. Univariate and multivariate Cox proportional hazards regression models were employed to assess potential predictors associated with pain recurrence.From May 2019 to May 2023, this study retrospectively collected 405 patients with TN: 265 underwent MVD and 140 received PBC. The overall cohort included 234 females (57.8%) with a median age of 68.0 years (range: 29.0-85.0 years), and baseline demographics, including symptom Duration, involved nerve branches, and comorbidities, showed no significant differences between groups. After a median follow-up of 34.0 months, pain recurrence occurred in 7.5% of the MVD group and 9.4% of the PBC group. Univariate Cox regression analysis revealed no significant difference in recurrence risk between PBC and MVD (Hazard Ratio [HR] 1.160, 95% Confidence Interval [CI] 0.553-2.434, P = 0.693). Procedure-related complications included facial numbness in 28.3% of MVD patients and 88.2% of PBC patients (P < 0.001), with bothersome numbness (BNI ≥ III) reported in 9.3% and 26.0%, respectively (P < 0.001). New or worsening masticatory dysfunction was observed in 2.2% of the MVD group compared to 7.9% of the PBC group (P = 0.011). No permanent neurological deficits or mortality occurred in either cohort.MVD offers durable pain relief with minimal sensory morbidity, while PBC achieves comparable pain relief at the cost of a significantly higher incidence of facial numbness. Treatment selection requires balancing efficacy, complications (particularly sensory side effects), and invasiveness.
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40991009What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.