Evidence map›Paper›PMID 40991097›Full record

ArticleDiscover oncology2025

From texture analysis to artificial intelligence: global research landscape and evolutionary trajectory of radiomics in hepatocellular carcinoma.

Xiong Teng, Quan-Neng Luo, Yi-Di Chen, Tao Peng

Abstract read
In one paragraph

Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiong Teng *Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.ORCID http://orcid.org/0000-0002-5535-5066
Quan-Neng Luo *Emergency and Disaster Medical Center, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, China.
Yi-Di ChenDepartment of Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China. chenyidi1152@126.com.ORCID http://orcid.org/0000-0001-6293-4624
Tao PengDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China. pengtaogmu@163.com.ORCID http://orcid.org/0000-0001-6133-7078

Funding

Key Laboratory of early Prevention & Treatment for regional High Frequency Tumor (Guangxi Medical University)-Ministry of Education nos. GKE-ZZ202213, GKE-ZZ202109 and GKE-ZZ202009National Natural Science Foundation of China No: 81560535, 81072321,81802874 and 30460143Scientific Research and Technology Development Program of Guangxi Zhuang Autonomous Region No.AD25069077The Open Project of Guangxi Key Laboratory of Enhanced Recovery after Surgery for Gastrointestinal Cancer GXEKL202405
6 · The paper itself

Abstract

backgroundHepatocellular carcinoma (HCC) poses a substantial global health burden with high morbidity and mortality rates. Radiomics, which extracts quantitative features from medical images to develop predictive models, has emerged as a promising non-invasive approach for HCC diagnosis and management. However, comprehensive analysis of research trends in this field remains limited.

methodsWe conducted a systematic bibliometric analysis of radiomics applications in HCC using literature from the Web of Science Core Collection (January 2006-April 2025). Publications were analyzed using CiteSpace, VOSviewer, R, and Python scripts to evaluate publication patterns, citation metrics, institutional contributions, keyword evolution, and collaboration networks.

resultsAmong 906 included publications, we observed exponential growth, particularly accelerating after 2019. A global landscape analysis revealed China as the leader in publication volume, while the USA acted as the primary international collaboration hub. Countries like South Korea and the UK demonstrated higher average citation impact. Sun Yat-sen University was the most productive institution. Research themes evolved from fundamental texture analysis and CT/MRI applications toward predicting microvascular invasion, assessing treatment response (especially TACE), and prognostic modeling, driven recently by the deep integration of artificial intelligence (AI) and deep learning. Co-citation analysis revealed core knowledge clusters spanning radiomics methodology, clinical management, and landmark applications, demonstrating the field's interdisciplinary nature.

conclusionRadiomics in HCC represents a rapidly expanding, AI-driven field characterized by extensive multidisciplinary collaboration. Future priorities should emphasize standardization, large-scale multicenter validation, enhanced international cooperation, and clinical translation to maximize radiomics' potential in precision HCC oncology.

Indexed as

Artificial intelligenceBibliometric analysisHepatocellular carcinomaRadiomicsResearch trends

Identifiers

PMID40991097
PMCPMC12460225

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.