Evidence map›Paper›PMID 40991176›Full record

ArticleInflammopharmacology2025

Jasmine sambac L. essential oil attenuates inflammation and pain via TRPV1.

Sahar Jaffal, Aluck Thipayarat, Samer Alqaraleh, Jakrapop Wongwiwat, Pattarin Supanivatin

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Article in Inflammopharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sahar JaffalPharmacy Department, College of Pharmacy, Amman Arab University, Amman, Jordan. sjaff333@gmail.com.ORCID http://orcid.org/0009-0002-3369-8954
Aluck Thipayarat *Department of Food Engineering, Faculty of Food Engineering, King Mongkut's University of Technology Thonburi, Bangkok, 10140, Thailand.
Samer AlqaralehDepartment of Basic Dental and Medical Sciences, Faculty of Dentistry, Mutah University, Al-Karak, Jordan.
Jakrapop WongwiwatDepartment of Mechanical Engineering, Faculty of Mechanical Engineering, King Mongkut's University of Technology Thonburi, Bangkok, 10140, Thailand.
Pattarin Supanivatin, 75 Soi Samanchan Barbos Prakanong, Klon Gtoey, Bangkok, 10110, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pain and inflammation are complex physiological responses. The drugs that are available in the market have multiple side effects. Thus, the search for safer effective therapeutics became a significant area of research. In this study, Jasmine sambac L. essential oil, which is aromatic and therapeutic in nature, has been studied for its potential anti-inflammatory and anti-nociceptive activities as well as its mechanism of action. The findings from this research indicated that the intraplantar (ipl) administration of jasmine essential oil to the animals produced anti-inflammatory effects in the carrageenan-induced paw edema model. In addition, jasmine essential oil showed significant inhibition of pain responses compared to the control group in the acetic acid-induced writhing test and immersion tail-flick test. These findings suggest that jasmine oil exhibits anti-nociceptive and anti-inflammatory effects in animals. More data are needed to determine its therapeutic value in human clinical trials. The anti-inflammatory and anti-nociceptive effects were mediated by the transient receptor potential vanilloid 1 (TRPV1), a key pain receptor. The chemical composition of jasmine essential oil was analyzed by gas chromatography-mass spectrometry (GC-MS) to determine the bioactive constituents that can be responsible for these effects. The results showed that the oil consists of active constituents with various therapeutic activities as reported in earlier studies. Thus, jasmine essential oil can be utilized as a complementary therapy for pain and inflammation treatment.

Indexed as

Anti-Inflammatory AgentsInflammationOils, VolatilePainPlant OilsTRPV Cation ChannelsAnalgesicsAnimalsCarrageenanDisease Models, AnimalEdemaGas Chromatography-Mass SpectrometryMaleMicePain MeasurementAnalgesicsAnti-Inflammatory AgentsCarrageenanOils, VolatilePlant OilsTRPV1 protein, mouseTRPV Cation ChannelsEssential oilInflammationJasmineMechanismPainTRPV1

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.