Evidence map›Paper›PMID 40993454›Full record

ArticleBulletin of experimental biology and medicine2025

Cytochrome C-Dependent Processes of Damage of Atherosclerotic Plaque Membranes Regulated by Anionic Phospholipids Containing Saturated and Unsaturated Fatty Acids.

G O Stepanov, V V Volkov, S P Konukhova, A A Struchkova, Yu A Vladimirov, A N Osipov, A V Tarasov, R S Akchurin, D M Galyautdinov, V P Masenko and 1 more

Abstract read
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In one paragraph

Article in Bulletin of experimental biology and medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

G O StepanovDepartment of General and Medical Biophysics, Medical Biological Faculty, Pirogov Russian National Research Medical University (Pirogov University), Ministry of Health of the Russian Federation, Moscow, Russia. stepanov_go@rsmu.ru.
V V VolkovDepartment of General and Medical Biophysics, Medical Biological Faculty, Pirogov Russian National Research Medical University (Pirogov University), Ministry of Health of the Russian Federation, Moscow, Russia.
S P KonukhovaDepartment of General and Medical Biophysics, Medical Biological Faculty, Pirogov Russian National Research Medical University (Pirogov University), Ministry of Health of the Russian Federation, Moscow, Russia.
A A StruchkovaDepartment of General and Medical Biophysics, Medical Biological Faculty, Pirogov Russian National Research Medical University (Pirogov University), Ministry of Health of the Russian Federation, Moscow, Russia.
Yu A VladimirovDepartment of General and Medical Biophysics, Medical Biological Faculty, Pirogov Russian National Research Medical University (Pirogov University), Ministry of Health of the Russian Federation, Moscow, Russia.
A N OsipovDepartment of General and Medical Biophysics, Medical Biological Faculty, Pirogov Russian National Research Medical University (Pirogov University), Ministry of Health of the Russian Federation, Moscow, Russia.
A V TarasovInstitute of Clinical Cardiology, National Medical Research Centre of Cardiology Named after Academician E. I. Chazov, Ministry of Health of the Russian Federation, Moscow, Russia.
R S AkchurinInstitute of Clinical Cardiology, National Medical Research Centre of Cardiology Named after Academician E. I. Chazov, Ministry of Health of the Russian Federation, Moscow, Russia.
D M GalyautdinovInstitute of Clinical Cardiology, National Medical Research Centre of Cardiology Named after Academician E. I. Chazov, Ministry of Health of the Russian Federation, Moscow, Russia.
V P MasenkoInstitute of Clinical Cardiology, National Medical Research Centre of Cardiology Named after Academician E. I. Chazov, Ministry of Health of the Russian Federation, Moscow, Russia.
O V StepanovaInstitute of Clinical Cardiology, National Medical Research Centre of Cardiology Named after Academician E. I. Chazov, Ministry of Health of the Russian Federation, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have shown that changes in the phospholipid and fatty acid composition of atherosclerotic plaques in the carotid arteries of patients who underwent carotid endarterectomy in combination with coronary artery bypass surgery are linked with the development of the pathological process and highlight the importance of cytochrome C-mediated induction of oxidation of membrane phospholipids. An increase of the steady-state equilibrium constant of cytochrome C with atherosclerotic membranes to 10

Indexed as

Cytochromes cFatty AcidsFatty Acids, UnsaturatedPhospholipidsPlaque, AtheroscleroticAgedCarotid ArteriesCoronary Artery BypassEndarterectomy, CarotidFemaleHumansLipid PeroxidationMaleMiddle AgedOxidation-ReductionCytochromes cFatty AcidsFatty Acids, UnsaturatedPhospholipidsAtherosclerotic plaqueCytochrome CEndarterectomyLipid peroxidation

Identifiers

PMID40993454

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.