ArticleBMC public health2025
Social risk profiles and diabetic kidney disease: prevalence and mortality in US adults.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Burden and trends of chronic kidney disease due to type 2 diabetes mellitus in China and G20 countries, 1990-2023: a comparative analysis.Frontiers in endocrinology · 2026Article
- Article
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6 authors.
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Abstract
backgroundDiabetic kidney disease (DKD) is a severe and prevalent complication of diabetes. Social contexts have been increasingly recognized as critical factors in the escalation and ongoing management of chronic diseases, including DKD. This study aimed to evaluate the connection between social risk profile (SRP) and DKD in United States.
methodsData were sourced from the National Health and Nutrition Examination Survey (1999-2018). DKD was defined as the coexistence of diabetes and chronic kidney disease (CKD). SRP scores, based on the number of positive measures, were categorized into four quartiles: low (0-2), lower-middle (3-4), upper-middle (5-6), and high (7-8). The associations of SRP with the prevalence and mortality of DKD were assessed.
resultsA total of 6,464 participants were included in the study, among them, 2,668 had DKD, and 1,153 died during a mean follow-up of 143 months. SRP scores were associated with the prevalence and mortality of DKD. Compared with high SRP scores, low SRP levels were related with a higher risk of DKD (OR, 1.86; 95% CI, 1.54 to 2.26, P < 0.0001). Higher SRP scores were associated with lower risks of mortality, including all-cause (HR, 0.84; 95% CI, 0.81-0.88; P < 0.0001), cardiovascular disease (HR, 0.85; 95% CI, 0.80-0.91; P < 0.0001), and diabetes-related mortality (HR, 0.86; 95% CI, 0.76-0.96; P = 0.009).
conclusionLower SRP scores showed a connection to higher DKD prevalence and worse outcomes, highlighting the potential importance of social risk screening and targeted interventions.
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