Evidence mapPaperPMID 40993952Full record

SynthesisCurrent diabetes reviews2026

The Impact of Yoga as an Adjunct to Standard Care on Glycemic Control, Insulin Resistance, Oxidative Stress, and Quality of Life in Individuals with or at Risk of Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis.

Danish Javed, Madhu Bhargavi Chandra, Varun Malhotra, Sofia Mudda, Padmavathi R, Vishnu Vardhan Karrothu, Madhu Babu Adusumilli, Santenna Chenchula

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Current diabetes reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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field-weighted citation impact
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Danish JavedAll India Institute of Medical Sciences, Bhopal, M.P, 462020, India.
Madhu Bhargavi ChandraWellstar Spalding Regional Hospital, Griffin, Georgia, 30224, USA.
Varun MalhotraAll India Institute of Medical Sciences, Bhopal, M.P, 462020, India.
Sofia MuddaAll India Institute of Medical Sciences, Bhopal, M.P, 462020, India.
Padmavathi RMediCiti Institute of Medical Sciences, Hyderabad, Telangana, 501401, India.
Vishnu Vardhan KarrothuAll India Institute of Medical Sciences, Bhopal, M.P, 462020, India.
Madhu Babu AdusumilliHCA Ocala, Florida, 34471, USA.
Santenna ChenchulaAll India Institute of Medical Sciences, Bhopal, M.P, 462020, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionType 2 Diabetes Mellitus (T2DM) is marked by insulin resistance and chronic hyperglycemia. Yoga, a complementary therapy, may improve metabolic outcomes when used with standard care. This systematic review and meta-analysis aimed to evaluate the effects of yoga on glycemic control, insulin resistance, oxidative stress, and psychological well-being in individuals with or at risk of T2DM.

methodsWe conducted a systematic search in PubMed, CAM-QUEST®, and the Cochrane Central Register following PRISMA guidelines. We included randomized controlled trials (RCTs) assessing yoga interventions (asanas, pranayama, kriyas, and meditation) alongside standard care. Primary outcomes were fasting blood glucose (FBS), postprandial blood glucose (PPBS), HbA1c, serum insulin, and HOMA-IR. Secondary outcomes included oxidative stress markers (glutathione, malondialdehyde [MDA], superoxide dismutase [SOD]) and psychological outcomes. Meta-analyses were conducted using random-effects models in RevMan 5.4.1.

resultsFourteen RCTs (n = 1,629 participants) were included. Yoga combined with standard care significantly improved FBS (SMD = -1.60; 95% CI: -2.27 to -0.92), PPBS (SMD = -2.16; p = 0.03), HbA1c (SMD = -0.92; 95% CI: -1.59 to -0.26), and HOMA-IR (SMD = -1.28; p = 0.002). MDA levels were significantly reduced, though glutathione and SOD showed no significant changes. Psychological well-being improved in several trials. DISCUSSION: Yoga appears effective in improving glycemic outcomes and insulin resistance in patients with or at risk of T2DM. It may also reduce oxidative stress and enhance psychological well- being, highlighting its potential as a holistic intervention.

conclusionYoga, when integrated with standard care, offers clinically relevant benefits in managing T2DM and related metabolic risks. Further high-quality, multi-centered trials using standardized protocols are needed to validate and generalize these findings.

Indexed as

Diabetes Mellitus, Type 2Glycemic ControlInsulin ResistanceOxidative StressQuality of LifeYogaBlood GlucoseHumansRandomized Controlled Trials as TopicBlood Glucosechronic hyperglycemiaglycemic controlinsulin resistanceoxidative stressType 2 diabetes mellitusyoga

Identifiers

PMID40993952

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.