Evidence map›Paper›PMID 40994669›Full record

ArticleJournal of clinical and translational science2025

Partial waiver of consent to overcome translational science barriers in neonatal clinical research.

Megha Sharma, Sarah E Diamond, Jenna Chancellor, Simon Chung, Andrew W Brown, D Micah Hester, Laura P James, Mario Schootman, Peter M Mourani, Sherry E Courtney

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and translational science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Megha SharmaDivision of Neonatology, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.ORCID https://orcid.org/0000-0002-9807-1856
Sarah E DiamondDivision of Neonatology, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Jenna ChancellorArkansas Children's Research Institute, Little Rock, AR, USA.
Simon ChungArkansas Children's Research Institute, Little Rock, AR, USA.
Andrew W BrownArkansas Children's Research Institute, Little Rock, AR, USA.
D Micah HesterDepartment of Medical Humanities and Bioethics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Laura P JamesDivision of Emergency Medicine, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.ORCID https://orcid.org/0000-0002-4266-3924
Mario SchootmanInstitute of Community Health and Innovation, Springdale, AR, USA.
Peter M MouraniArkansas Children's Research Institute, Little Rock, AR, USA.
Sherry E CourtneyDivision of Neonatology, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prospective consent in neonatal research poses significant challenges, particularly during urgent, time-sensitive clinical windows of study enrollment. This is especially true at referral centers for large geographic regions. A partial waiver of consent offers a potential translational science approach to enhance access to research participation in critically ill neonates. We compared enrollment rates in a study evaluating pulse oximetry accuracy across neonates with varying skin pigmentation before and after implementing a partial waiver of consent. Overall enrollment increased significantly without creating a racial disparity in enrollment, thereby improving generalizability and efficiency in neonatal clinical research.

Indexed as

clinical trialsconsentenrollmentequityNeonates

Identifiers

PMID40994669
PMCPMC12454670

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.