ArticleFrontiers in cellular and infection microbiology2025
Assessment of the relationship between gut microbiota, inflammatory markers, and colorectal cancer.
Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed.
- Del immune V and microbiome restructuring in colorectal cancer surgery: a randomized double blind placebo controlled trial.Frontiers in cellular and infection microbiology · 2026Trial
- Immunometabolic Biomarkers in Colorectal Cancer: An Exploratory Diagnostic Evaluation of PBEF/NAMPT, Chemerin, and Osteopontin.International journal of molecular sciences · 2026Article
- Associations of Low-Carbohydrate High-Fat Dietary Patterns with Colorectal Tumor Burden and Gut Microbial Dynamics in an AOM/DSS Mouse Model.International journal of molecular sciences · 2026Article
- Trend of C-Reactive protein after colorectal surgery may increase predictive value of anastomotic leak: a prospective analysis.BMC surgery · 2026Article
- A Glutathione-Responsive Prodrug Nanosystem for Colorectal Cancer: Synergistic Co-Delivery of Paclitaxel and Curcumin to Combat Multidrug Resistance and Reinvent the Immunosuppressive Microenvironment.Biomaterials research · 2026Article
- Gut microbiota-derived indole metabolites in colorectal cancer: potential links to PI3K/AKT signaling pathway.Frontiers in microbiology · 2026Review
Corrections and comments
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Authors and funding
1 author.
Funding
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Abstract
Objective: This study aims to evaluate the correlation between inflammation and gut microbiota characteristics in patients with colorectal cancer (CRC) through a retrospective study. Methods: This cross-sectional, non-interventional study included a total of 200 subjects, of which 150 were colorectal cancer (CRC) patients and 50 were healthy individuals. The study retrospectively reviewed hospital and laboratory archives and records from 2015 to 2020. Gut microbiota was analyzed using 16S rRNA sequencing. Inflammatory markers, including C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), and interleukin-beta (IL-1β), were measured using enzyme-linked immunosorbent assay (ELISA). Logistic regression analysis was used to evaluate the relationship between gut microbiota, inflammatory markers, and CRC. Results: Subjects in the colorectal cancer (CRC) group exhibited a higher proportion of Firmicutes (47.2% Conclusion: There is a significant correlation between changes in gut microbiota composition and cytokine levels with the risk of colorectal cancer (CRC).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.