Evidence map›Paper›PMID 40995322›Full record

ReviewTaiwan journal of ophthalmology

Optical coherence tomography and optical coherence tomography angiography in systemic disease.

David J Merriott, Devayu Parikh, Michael J Najac, Luis Muncharaz Duran, Affan Haq, Richard B Rosen, Toco Y P Chui

Abstract readReview
In one paragraph

Review in Taiwan journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. AI-driven multimodal retinal imaging for early detection and risk stratification of vascular and neurodegenerative diseases.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David J MerriottDepartment of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA.
Devayu ParikhDepartment of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA.
Michael J NajacDepartment of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA.
Luis Muncharaz DuranDepartment of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA.
Affan HaqDepartment of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA.
Richard B RosenDepartment of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA.
Toco Y P ChuiDepartment of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA.

Funding

SCD REVIVE - Retina to Evaluate Vaso occlusion In the Vasculature of the EyeR01HL159116 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Yuen Ping Toco Chui, Jeffrey Avins Glassberg · 2022 to 2026
$4.0M
Characterization of vascular responses to intravitreal anti-VEGF injections in diabetic retinopathyR01EY027301 · NEI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Yuen Ping Toco Chui · 2017 to 2026
$4.0M
NEI NIH HHS R01 EY027301NHLBI NIH HHS R01 HL159116
6 · The paper itself

Abstract

Optical coherence tomography (OCT) is an integral component of present-day ophthalmologic practice. As use of OCT has increased in popularity and frequency of use, a growing number of systemic diseases are now known to have associated findings on both OCT and OCT angiography (OCTA). This review was written to discuss how a multitude of cardiovascular, neurodegenerative, neoplastic, infectious, and autoimmune diseases manifest on OCT and OCTA. The findings thus far highlight the potential utility of OCT and OCTA for diagnosing and monitoring progression of these disease processes. Many current studies are limited by small sample sizes, varying image processing algorithms, image artifact, and differing machines used to acquire images, underscoring the need for further research with increased patient numbers and standardized image acquisition and image processing protocols. Despite these current limitations, the steadily increasing volume of data suggests that there will ultimately be a role for both OCT and OCTA to noninvasively monitor the progression of systemic disease over time.

Indexed as

Cardiovascular diseasesdiagnosisoptical coherence tomography

Identifiers

PMID40995322
PMCPMC12456916

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.