ArticleJournal of cosmetic dermatology2025
Evaluation of the Efficacy and Safety of Single-Needle Radiofrequency in Patients With Facial Sebaceous Hyperplasia: A Retrospective Study.
Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Evaluation of the Efficacy and Safety of Single-Needle Radiofrequency in Patients With Facial Sebaceous Hyperplasia: A Retrospective Study.Journal of cosmetic dermatology · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
BACKGROUND AND
aimsSebaceous hyperplasia is a prevalent comorbidity in dermatology. However, there is a notable absence of an effective and safe treatment modality in current clinical practice. This study aimed to evaluate the efficacy and safety of single-needle radiofrequency for treating facial sebaceous hyperplasia.
methodsA retrospective study was undertaken, enrolling patients diagnosed with facial sebaceous hyperplasia that spanned from December 2021 to August 2023 in the department of dermatology, Zhongshan Hospital (Xiamen), Fudan University. Dermoscopy was employed for the objective evaluation before treatment and at 4-week intervals following each treatment session. The Pain Visual Analogue Scale was assessed by each patient immediately after treatment. The treatment endpoint was defined as the absence of more than 50% visible white-yellowish globules under dermoscopy. Treatment responses were classified as optimal, good, and poor, determined by the regression rate of skin lesions, set at over 90%, 50%-90%, and below 50%, respectively. All patients were subsequently subjected to follow-up examinations every 4 weeks for a period of 6 months, along with an assessment of any complications. Patients underwent systematic follow-up assessments at 24-72 h for acute complications and every 4 weeks for 6 months to evaluate long-term outcomes.
resultsA total of 45 patients were included, with a male-to-female ratio of 1.8:1. The mean age of onset was 42.9 ± 9.6 years. Forty-four patients (97.8%) achieved optimal outcomes, while one patient (2.2%) showed a good result. The average number of treatments required was 2.2 ± 0.8. Male patients required more treatment sessions and a wider pulse width compared to female patients (p < 0.05). During the follow-up, only one case (2.2%) experienced a relapse. Complications following treatment included redness (100%) and crusting (8.9%). The average treatment pain score was recorded as 2.6 ± 0.5.
conclusionThe use of single-needle radiofrequency proves to be an effective and safe treatment for patients with sebaceous hyperplasia. Dermoscopy emerges as a valuable auxiliary tool for evaluation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.