Evidence map›Paper›PMID 40996800›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

A diverse family of bacterial deubiquitinases is defined by the

Jeffrey K Duncan-Lowey, Craig R Roy

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jeffrey K Duncan-LoweyDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536.ORCID 0000-0002-3615-9596
Craig R RoyDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536.ORCID 0000-0003-4490-440X

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007205 · NIGMS · YALE UNIVERSITY · PI KAZMIERCZAK, BARBARA I · 1985 to 2019
$42.9M
The Role of Coxiella Effector Proteins in Infection and DiseaseR56AI182383 · NIAID · YALE UNIVERSITY · PI ROY, CRAIG R. · 2024 to 2024
$625k
6500 QTrap Mass Spectrometer for Yale UniversityS10OD018034 · OD · YALE UNIVERSITY · PI MANE, SHRIKANT M · 2014 to 2014
$514k
Defining epistatic interactions among Coxiella burnetii effector proteins using a CRISPRi approachR21AI171333 · NIAID · YALE UNIVERSITY · PI ROY, CRAIG R. · 2022 to 2023
$461k
Modulation of Host Cell Function by Coxiella BurnetiiR56AI064559 · NIAID · YALE UNIVERSITY · PI ROY, CRAIG R. · 2014 to 2014
$416k
An Ultra-Performance Liquid Chromatography System to Support Metabolomics at Yale UniversityS10OD019967 · OD · YALE UNIVERSITY · PI LAM, TUKIET T · 2015 to 2015
$135k
The role of a Coxiella burnetii effector protein that inhibits RIG-I signalingF30AI181493 · NIAID · YALE UNIVERSITY · PI Jeffrey Kardas Duncan-Lowey · 2024 to 2026
$133k
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) F30AI181493HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R21AI171333HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R56AI182383HHS | NIH | National Institute of General Medical Sciences (NIGMS) T32GM007205NIAID NIH HHS F30 AI181493NIAID NIH HHS R21 AI171333NIAID NIH HHS R56 AI064559NIAID NIH HHS R56 AI182383NIGMS NIH HHS T32 GM007205NIH HHS S10 OD018034NIH HHS S10 OD019967
6 · The paper itself

Abstract

The obligate intracellular pathogen

Indexed as

Bacterial ProteinsCoxiella burnetiiDeubiquitinating EnzymesHumansPhylogenyUbiquitinBacterial ProteinsDeubiquitinating EnzymesUbiquitinbacterial effectorsbacterial pathogenesisdeubiquitinasesintracellular pathogenstype IV secretion

Identifiers

PMID40996800
PMCPMC12501173

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.