ArticlePloS one2025
Association of cognitive function with frailty, nutritional status, and quality of life in older adults with mild cognitive impairment.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Effects of synergistic tongue and chin resistance training on swallowing function, oral intake, and cognitive function in community-dwelling elderly individuals with frailty: a double-blind randomised controlled trial.Journal of global health · 2025Trial
- Multidimensional assessment of cognitive function in community-dwelling older adults: fNIRS dual-task assessment and nutritional evaluation in Japanese salons.Frontiers in public health · 2026Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn older adulthood, mild cognitive impairment is an intermediate stage between normal aging and dementia, making its detection crucial. Therefore, this study aims to analyze the associations between cognitive function and frailty, nutritional status, and quality of life in older adults with mild cognitive impairment.
methodsThis work was conducted through a cross-sectional, analytical study involving 129 adults diagnosed with mild cognitive impairment, with a mean age of 68.07 ± 4.22. For cognitive assessment, the Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Isaac Verbal Fluency Test, Trail Making Test (TMT), D2 Test of Attention (D2 Test), and Digit Symbol Substitution Test (DSST) were completed; clinical and functional status was assessed using the frailty (FRAIL), Mini Nutritional Assessment (MNA), and life quality 36-Item Short Form Survey (SF-36) questionnaires.
resultsRegarding overall cognitive performance, the presence of mild cognitive impairment was confirmed in the sample, as was the slowing of executive functions. Regarding selective attention, participants obtained an average of 138.30 points [SD = 4.30] in the D2 test, while the average score for processing speed measured using the DSST was 43.60 [SD = 3.50]. Regarding clinical and functional variables, the average FRAIL score was 2.26 [SD = 1.67], suggesting a high prevalence of frailty and pre-frailty; the average nutritional status was 27.91 [SD = 1.88], a range of adequate nutritional status. Finally, quality of life showed an average of 61.40 [SD = 14.87], indicating a moderate level. DISCUSSION: This study shows that frailty, nutritional status, and quality of life are closely related to mild cognitive impairment. These results reinforce the need for early and multidimensional interventions that contribute to preserving the quality of life.
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