Evidence map›Paper›PMID 40998874›Full record

ArticleScientific reports2025

Sustained abstinence after a methamphetamine-specific treatment program for pregnant and parenting women.

Maximilian Pilhatsch, Fabienne Körner, Maik Spreer, Arvid Pietsch, Alexa Fries, Johannes Petzold

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Substance use disorders and addictions.Scientific reports · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maximilian PilhatschDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Faculty of Medicine, Dresden University of Technology, Dresden, Germany. maximilian.pilhatsch@ukdd.de.ORCID http://orcid.org/0000-0003-4323-3309
Fabienne KörnerDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Faculty of Medicine, Dresden University of Technology, Dresden, Germany.
Maik SpreerDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Faculty of Medicine, Dresden University of Technology, Dresden, Germany.ORCID http://orcid.org/0000-0001-8436-8520
Arvid PietschDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Faculty of Medicine, Dresden University of Technology, Dresden, Germany.ORCID http://orcid.org/0009-0001-7222-6290
Alexa FriesDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Faculty of Medicine, Dresden University of Technology, Dresden, Germany.ORCID http://orcid.org/0009-0002-3560-5870
Johannes PetzoldDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Faculty of Medicine, Dresden University of Technology, Dresden, Germany.ORCID http://orcid.org/0000-0003-4163-9014

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The treatment of methamphetamine use disorder (MUD) poses a significant challenge due to high rates of treatment discontinuation, substance use recurrence, and socioeconomic adversity. 'Mummy, think of me' (MAMADAM, an acronym from the German "Mama, denk an mich"), a treatment program specifically designed for pregnant women and young mothers with substance use disorders, has shown positive results regarding treatment efficacy and retention of child custody. This study aimed to evaluate the long-term sustainability of the MAMADAM intervention, which has not yet been examined. For this retrospective follow-up study, former patients with MUD who were pregnant and/or parenting women at the time of MAMADAM treatment were contacted by telephone. We analyzed whether self-reported abstinence after discharge from MAMADAM was associated with patient characteristics at admission to MAMADAM. Of the 114 eligible women, 39 participated in the follow-up interview, on average, 4.5 years after completing MAMADAM. Of these, 16 (41%) reported sustained abstinence from all addictive substances, excluding tobacco. At 12 and 18 months after discharge from MAMADAM, 9/39 (23%) and 11/39 (28%) women, respectively, reported at least one instance of substance use, including alcohol but excluding tobacco. Women who reported recurrences of substance use were significantly more likely to have more underage children, live apart from at least one minor, and consume methamphetamine for longer before MAMADAM than women with sustained abstinence. Cox regression, controlling for the duration of MAMADAM treatment, indicated that a longer history of methamphetamine use at admission to MAMADAM was associated with a shorter period of abstinence from all addictive substances (excluding tobacco) following discharge. The MAMADAM program is effective and sustainable in supporting long-term abstinence among pregnant and parenting women with MUD, indicating that pregnancy and parenthood can serve as turning points for promoting the necessary behavioral changes for recovery from addiction. Some women remain at elevated risk of relapse due to the vulnerabilities identified in this study. Future research should investigate whether stronger collaborations with government and community agencies can help these women maintain long-term abstinence.

Indexed as

Amphetamine-Related DisordersMethamphetamineParentingAdultFemaleFollow-Up StudiesHumansPregnancyRetrospective StudiesTreatment OutcomeYoung AdultMethamphetamine

Identifiers

PMID40998874
PMCPMC12464192

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.