Evidence map›Paper›PMID 40999410›Full record

ArticleBMC oral health2025

Beyond failure: a case report on brain state changes during virtual reality-induced hypnosis in pediatric patient.

Marco Mazzoni, Michela Mossuto, Gianclaudio Falasco, Tiziana Coin, Claudio Gallo, Carla Mucignat

Abstract readCase Reports
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marco MazzoniAnesthesiology Department, Piove di Sacco Hospital, AULSS 6 Euganea, Piove di Sacco (Padova), Italy.
Michela MossutoCommunity Dentistry Unit, Piove di Sacco Hospital, AULSS 6 Euganea, Piove di Sacco (Padova), Italy.
Gianclaudio FalascoAnesthesiology Department, Piove di Sacco Hospital, AULSS 6 Euganea, Piove di Sacco (Padova), Italy.
Tiziana CoinCommunity Dentistry Unit, Piove di Sacco Hospital, AULSS 6 Euganea, Piove di Sacco (Padova), Italy.
Claudio GalloCommunity Dentistry Unit, Piove di Sacco Hospital, AULSS 6 Euganea, Piove di Sacco (Padova), Italy. claudio.gallo@aulss6.veneto.it.
Carla MucignatDepartment of Molecular Medicine, University of Padova, Padova, Italy. carla.mucignat@unipd.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundManagement of fear in anxious patients is challenging, particularly in children. Virtual reality induced hypnosis may help during the procedures, changing vital parameters and brain states. Modifications in brain activity can be easily traced with wearable instruments. CASE PRESENTATION: An 11-years old boy was scheduled for avulsion of teeth 15 and 25, which were misplaced in the hard palate. Due to his fear of procedure, he was exposed to virtual reality-induced hypnosis. The brain state was continuously monitored, showing light sedation, associated to low spectral edge frequency values, below 20 Hz, indicating a relaxed/hypnotic state. In both sessions, the electrical activity was higher in the right hemisphere compared to the left, which is conceivable in hypnotic state. During the first session, a technical problem ensued, which was detected by the patient and readily managed with additional anesthesia. Despite the negative experience, one week later the hypnotic state was readily induced and tooth extraction was accomplished without any problem.

conclusionsVirtual reality-induced hypnotic state may be an easy and safe procedure to use with anxious patients even in pediatric age. If coupled to brain state monitoring, also adverse events can be promptly managed. In addition, hypnotic state may be induced also after the negative experience due to unexpected problems, prompting for the use of this technique in the dental setting also after initial, partial failure.

Indexed as

BrainDental AnxietyHypnosisHypnosis, DentalVirtual RealityChildElectroencephalographyHumansMaleTooth ExtractionElectroencephalographyHypnosisPediatric dentistry

Identifiers

PMID40999410
PMCPMC12465314

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.