Evidence mapPaperPMID 40999974Full record

ArticleMolecular medicine reports2025

Atractylodin inhibits ferroptosis in sepsis‑induced acute gastrointestinal injury via SIRT3/PRDX3.

Yun-Xia Hu, Ming-Qi Chen, Jian-Lin Wang, Tao Wu, Hai-Dong Zhang, Tong-Tong Li, Hui Gao, Yu Bai

Abstract read
In one paragraph

Article in Molecular medicine reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yun-Xia HuDepartment of Intensive Care Medicine, Liyang Branch of Jiangsu Provincial Hospital of Chinese Medicine, Changzhou, Jiangsu 213300, P.R. China.
Ming-Qi ChenDepartment of Intensive Care Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210004, P.R. China.
Jian-Lin WangDepartment of Intensive Care Medicine, Liyang Branch of Jiangsu Provincial Hospital of Chinese Medicine, Changzhou, Jiangsu 213300, P.R. China.
Tao WuDepartment of Intensive Care Medicine, Liyang Branch of Jiangsu Provincial Hospital of Chinese Medicine, Changzhou, Jiangsu 213300, P.R. China.
Hai-Dong ZhangDepartment of Intensive Care Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210004, P.R. China.
Tong-Tong LiDepartment of Intensive Care Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210004, P.R. China.
Hui GaoDepartment of Intensive Care Medicine, Liyang Branch of Jiangsu Provincial Hospital of Chinese Medicine, Changzhou, Jiangsu 213300, P.R. China.
Yu BaiClinical Department of Integrated Traditional Chinese and Western Medicine, School of Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrointestinal injury (GI) is a significant concern in various medical contexts, particularly in patients undergoing antiplatelet therapy, experiencing trauma, or dealing with the effects of medications. The present study investigated the effect of atractylodin, a bioactive compound derived from

Indexed as

FerroptosisFuransGastrointestinal DiseasesSepsisSirtuin 3AnimalsApoptosisDisease Models, AnimalHumansMaleMembrane Potential, MitochondrialMiceMice, Inbred C57BLMitochondriaatractylodinFuransSirt3 protein, mouseSirtuin 3acute gastrointestinal injuryatractylodinferroptosisperoxiredoxin‑3sirtuin‑3

Identifiers

PMID40999974
PMCPMC12512527

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.