Evidence map›Paper›PMID 41000372›Full record

ArticleClinical Medicine Insights. Oncology2025

The Effect of Bladder and Rectum Volume Changes on Exposed Organ Volume During Intensity-Modulated Radiotherapy for Cervical Cancer.

Hui Liu, Zixian Zhang, Xuan Guo, Tong Wang, Jiang Hu, Jianhui Shao, Feng Chi, Huilang He

Abstract read
In one paragraph

Article in Clinical Medicine Insights. Oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hui LiuState Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, P. R. China.
Zixian ZhangState Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, P. R. China.
Xuan GuoState Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, P. R. China.
Tong WangState Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, P. R. China.
Jiang HuState Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, P. R. China.
Jianhui ShaoState Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, P. R. China.
Feng ChiState Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, P. R. China.
Huilang HeState Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, P. R. China.ORCID https://orcid.org/0000-0001-7353-2241

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This retrospective cohort study aims to study the changes of the exposed volume of the bladder and rectum under different filling states, and to clarify the influences of the morphing organs on themselves and each other, to provide the basis for reducing the risk of organ damage by intensity-modulated radiotherapy (IMRT) for cervical cancer. Methods: A retrospective analysis was performed on 24 patients with cervical cancer who received IMRT. Before radiotherapy, a comfortably full bladder and active defecation was ensured for all patients, and interative cone-beam computed tomography (iCBCT) was performed to delineate the bladder, rectum, and small intestine. The filling degree of the bladder, rectum, and small intestine and their intersection with the planned target volume were recorded. Results: 83.44% of patients exhibited reduced bladder volume during treatment. When the planned bladder volume was 400-500 cc, the bladder volume changed the least during treatment (F = 58.39, Conclusion: Comfortable bladder and active defecation regimens may not keep bladder and rectal stability. Targeting a planned bladder volume of 400 to 500cc minimizes intrafraction variability. Strategic bladder filling optimization may mitigate small intestine exposure.

Indexed as

bladder/rectal fullnessCervical cancercorrelationintensity-modulated radiation therapyvolume of exposure

Identifiers

PMID41000372
PMCPMC12457747

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.