Evidence map›Paper›PMID 41000381›Full record

ArticleFrontiers in immunology2025

The N-terminal domain of

Qiang Li, Huimin Wang, Yuehui Cui, Zongyang Huang, Xuedi Zhang, Rongze He, Cheng He

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qiang LiNational Key Lab of Veterinary Public Health Security, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Huimin WangNational Key Lab of Veterinary Public Health Security, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Yuehui CuiNational Key Lab of Veterinary Public Health Security, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Zongyang HuangNational Key Lab of Veterinary Public Health Security, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Xuedi ZhangNational Key Lab of Veterinary Public Health Security, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Rongze HeNational Key Lab of Veterinary Public Health Security, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Cheng HeNational Key Lab of Veterinary Public Health Security, College of Veterinary Medicine, China Agricultural University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Methods and Results: This study demonstrates that both Discussion: Our findings indicate that Pmp19G regulates macrophage autophagy through distinct mechanisms in early and late phases: activation of the NOD1-ATG16L1 signaling pathway initiates early autophagy, while enhanced RAB7 recruitment inhibits autophagosome-lysosome fusion during late autophagy. Collectively, Pmp19G-involved manipulation of the autophagic process represents a critical strategy employed by

Indexed as

AutophagyAutophagy-Related ProteinsBacterial ProteinsChlamydophila psittaciMacrophagesNod1 Signaling Adaptor ProteinPsittacosisrab GTP-Binding ProteinsAnimalsHost-Pathogen InteractionsHumansMicerab7 GTP-Binding ProteinsSignal TransductionAtg16l1 protein, mouseAutophagy-Related ProteinsBacterial ProteinsNod1 protein, mouseNod1 Signaling Adaptor Proteinrab7 GTP-Binding Proteinsrab7 GTP-binding proteins, mouserab GTP-Binding ProteinsautophagyChlamydia psittaciimmune evasionmacrophagesNOD1Pmp19G

Identifiers

PMID41000381
PMCPMC12457404

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.