Evidence map›Paper›PMID 41000721›Full record

ArticlebioRxiv : the preprint server for biology2025

Cosmopolitan inversions have a major impact on trait variation and the power of different GWAS approaches to identify associations.

Benedict Adam Lenhart, Alan O Bergland

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Benedict Adam LenhartDepartment of Biology, University of Virginia, Charlottesville, VA 22904.ORCID 0000-0002-1533-5386
Alan O BerglandDepartment of Biology, University of Virginia, Charlottesville, VA 22904.ORCID 0000-0001-7145-7575

Funding

The genetic and physiological architecture of rapid and cyclic adaptationR35GM119686 · NIGMS · UNIVERSITY OF VIRGINIA · PI BERGLAND, ALAN OLAV · 2016 to 2020
$1.9M
NIGMS NIH HHS R35 GM119686
6 · The paper itself

Abstract

The ability of genomic inversions to reduce recombination and generate linkage can have a major impact on genetically based phenotypic variation in populations. However, the increase in linkage associated with inversions can create hurdles for identifying associations between loci within inversions and the traits they impact. As a consequence, the role of inversions in mediating genetic variation in complex traits remains to be fully understood. This study uses the fruit fly

Indexed as

Drosophila melanogasterGWASInversions

Identifiers

PMID41000721
PMCPMC12458207

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.