Evidence map›Paper›PMID 41001539›Full record

ArticleResearch square2025

Correlation of physiological stress as measured by heart rate and blood pressure variability and self-reported anxiety.

Gurjeet Birdee, Hui Nian, Sachin Paranjape, Robert Abraham, Andre Diedrich, Kerry Kinney, Alfredo Gamboa

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In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gurjeet BirdeeVanderbilt University Medical Center.ORCID 0000-0001-5776-1095
Hui NianVanderbilt University Medical Center.
Sachin ParanjapeVUMC: Vanderbilt University Medical Center.
Robert AbrahamVUMC: Vanderbilt University Medical Center.
Andre DiedrichVUMC: Vanderbilt University Medical Center.
Kerry KinneyVUMC: Vanderbilt University Medical Center.
Alfredo GamboaVUMC: Vanderbilt University Medical Center.

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
Breathing Interventions for Relaxation: Dosing through Extended ExhaleR61AT009340 · NCCIH · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BIRDEE, GURJEET SINGH · 2016 to 2017
$859k
NCATS NIH HHS UL1 TR002243NCCIH NIH HHS R61 AT009340
6 · The paper itself

Abstract

Background: Despite lack of data, there is an assumption that anxiety symptoms correspond with a physiological stress response with decreased parasympathetic and increased sympathetic nervous system. Objective: To examine whether self-reported measures of anxiety correlate with physiological stress. Methods: We performed a secondary analysis of data collected from a 12-week clinical trial on slow breathing that examined the changes in psychological and physiological stress (n = 88). Psychological stress was assessed with PROMIS Anxiety CAT. Physiological stress was assessed by spectral analysis of heart rate including RMSSD, LF Results: Despite a decrease in mean PROMIS Anxiety from baseline to 12 weeks (-4.85 S.D. ± 5.53) from slow breathing, we found a low correlation between PROMIS Anxiety and physiological measures of stress for specific time points or changes over time. Measures of autonomic tone, including LF Conclusion: We report a lack of correlation between self-reported anxiety and physiological measures of stress despite reductions in self-reported stress after a behavioral intervention for relaxation.

Identifiers

PMID41001539
PMCPMC12458539

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.