Evidence map›Paper›PMID 41001548›Full record

ArticleResearch square2025

Tonic Dopamine Sensing Reveals a D2/D3 Mediated Dopamine Response to Raclopride in ClockΔ19 Mice Model.

Bingchen Wu, Elisa Castagnola, Elaine Robbins, Mariya Kaminsky, Subramaniam Sanker, Colleen McClung, Xinyan Tracy Cui

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Bingchen WuUniversity of Pittsburgh.
Elisa CastagnolaLouisiana Tech University.
Elaine RobbinsUniversity of Pittsburgh.
Mariya KaminskyUniversity of Pittsburgh.
Subramaniam SankerUniversity of Pittsburgh.
Colleen McClungUniversity of Pittsburgh.
Xinyan Tracy CuiUniversity of Pittsburgh.

Funding

Role of NPAS2 in the nucleus accumbens in drug addictionR01DA039865 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MCCLUNG, COLLEEN A · 2015 to 2024
$3.9M
Selective HDAC inhibition and therapeutic target genes: Identification of novel treatments for Bipolar DisorderR01MH106460 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MCCLUNG, COLLEEN A · 2016 to 2024
$3.6M
Efficiency and Safety of Microstimulation Via Different Electrode MaterialsR01NS110564 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CUI, XINYAN TRACY · 2019 to 2024
$3.1M
Ultra sensitive and flexible MEAs for chronic dopamine detection at both tonic and phasic levelsR21DA049592 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CUI, XINYAN TRACY · 2019 to 2020
$428k
Laser Induced NanoCarbon Multielectrode Arrays for Neurotransmitter SensingR21NS123937 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BEDEWY, MOSTAFA, CUI, XINYAN TRACY · 2021 to 2021
$423k
NIDA NIH HHS R01 DA039865NIDA NIH HHS R21 DA049592NIMH NIH HHS R01 MH106460NINDS NIH HHS R01 NS110564NINDS NIH HHS R21 NS123937
6 · The paper itself

Abstract

The circadian rhythm regulates physiological and behavioral processes, with disruptions linked to metabolic and neuropsychiatric disorders. Circadian genes play a crucial role in the regulation of dopaminergic signaling, yet the underlying molecular mechanisms remain unclear. This study investigates how the

Identifiers

PMID41001548
PMCPMC12458542

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.