Evidence map›Paper›PMID 41002012›Full record

ArticleAngewandte Chemie (International ed. in English)2025

Silylative Amide to Nitrile Conversion Mediated by Simple Lanthanide-Organoamides: Scope and Mechanism.

Zhiyu Feng, Qingheng Lai, Yuang Wang, Alessandro Motta, Yosi Kratish, Tobin J Marks

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhiyu FengDepartment of Chemistry, Northwestern University, 2145 Sheridan Rd, Evanston, Illinois, 60208-3113, USA.
Qingheng LaiDepartment of Chemistry, Northwestern University, 2145 Sheridan Rd, Evanston, Illinois, 60208-3113, USA.
Yuang WangDepartment of Chemistry, Northwestern University, 2145 Sheridan Rd, Evanston, Illinois, 60208-3113, USA.
Alessandro MottaDipartimento di Scienze Chimiche, Università di Roma "La Sapienza" and INSTM, UdR Roma, Roma, I-00185, Italy.
Yosi KratishDepartment of Chemistry, Northwestern University, 2145 Sheridan Rd, Evanston, Illinois, 60208-3113, USA.
Tobin J MarksDepartment of Chemistry, Northwestern University, 2145 Sheridan Rd, Evanston, Illinois, 60208-3113, USA.ORCID https://orcid.org/0000-0001-8771-0141

Funding

NSF CAT CHE-2247666Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource NSFECCS-2025633
6 · The paper itself

Abstract

Efficient, selective, and environmentally benign catalytic nitrile synthesis is attractive for pharmaceuticals, specialty chemicals and materials, and large-scale industrial applications. In this regard, metal-catalyzed silylative conversion of primary amides to nitriles is emerging as a promising approach. This contribution reports the utilization of readily available lanthanide-organic amido precatalysts, Ln[N(SiMe

Indexed as

DFT analysisKinetic/Mechanistic evaluationNitrile synthesisOrganolanthanide

Identifiers

PMID41002012
PMCPMC12603988

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.