Evidence map›Paper›PMID 41002015›Full record

SynthesisJournal of hypertension2026

Arterial spin labeling MRI in assessing cerebral blood flow changes due to hypertension: a systematic review.

Sathya Sabina Muthu, Suresh Sukumar, Rajagopal Kadavigere, Shivashankar K N, K Vaishali, Ramesh Babu M G, Hari Prakash Palaniswamy, Abhimanyu Pradhan, Winniecia Dkhar, Nitika C Panakkal and 3 more

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of hypertension, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sathya Sabina MuthuDepartment of Medical Imaging Technology, Manipal College of Health Professions.
Suresh SukumarDepartment of Medical Imaging Technology, Manipal College of Health Professions.
Rajagopal KadavigereDepartment of Radiodiagnosis and Imaging, Kasturba Medical College.
Shivashankar K NDepartment of General Medicine, Kasturba Medical College.
K VaishaliDepartment of Physiotherapy, Manipal College of Health Professions.
Ramesh Babu M GDepartment of Department of Basic Medical Sciences, MMMC.
Hari Prakash PalaniswamyDepartment of Speech and Hearing, Manipal College of Health Professions.
Abhimanyu PradhanDepartment of Medical Imaging Technology, Manipal College of Health Professions.
Winniecia DkharDepartment of Medical Imaging Technology, Manipal College of Health Professions.
Nitika C PanakkalDepartment of Medical Imaging Technology, Manipal College of Health Professions.
Sneha RavichandranDepartment of Medical Imaging Technology, Manipal College of Health Professions.
Dilip ShettigarDepartment of Medical Imaging Technology, Manipal College of Health Professions.
Poovitha Shruthi ParamashivaDivision of Yoga, Centre for Integrative Medicine and Research, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertension is a significant risk factor for cerebrovascular diseases, affecting cerebral blood flow (CBF) and brain health. Reduced CBF in hypertensive individuals is linked to cognitive decline and neurodegenerative diseases. Arterial spin labeling (ASL) MRI offers a noninvasive method to assess these changes. This systematic review consolidates evidence on the impact of hypertension on CBF using ASL-MRI. A comprehensive search across PubMed, Scopus, Embase, and Web of Science, following PRISMA 2020 guidelines, included studies on adults with hypertension reporting CBF measurements. Findings indicate that hypertension reduces CBF in various brain regions, with improvements seen after antihypertensive treatment. ASL-MRI may be a valuable tool for monitoring treatment effectiveness and brain health. However, most studies were conducted in high-income countries and elderly populations, emphasizing the need for further research in younger and low-income settings. Early CBF assessment using ASL-MRI could aid in timely interventions.

Indexed as

Cerebrovascular CirculationHypertensionMagnetic Resonance ImagingSpin LabelsBrainHumansSpin Labelsarterial spin labeling MRIblood pressurebrainbrain perfusioncerebral blood flowcerebral perfusionhigh blood pressurehypertensionneurovascular disease

Identifiers

PMID41002015
PMCPMC12672045

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.